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Incidence of growth hormone gene polymorphisms in strains of chicken selected for abdominal fat content or resistance to avian leukosis virus or Marek's disease

Chicken strains divergently selected for either abdominal fat deposition, avian leukosis (ALV) resistance or Marek's disease (MD) resistance were analyzed for restriction fragment length polymorphism (RFLP) in the growth hormone gene (GH). A total of four polymorphisms were identified, one at a SacI restriction site (PS1) and three at MspI restriction sites (PM1-PM3). Restriction mapping indicated that all polymorphisms were in exons and/or introns and not in flanking regions of the gene. Selection for abdominal fat composition significantly affected the frequency of polymorphisms at PM2, but not at the other restriction sites (p $<$ 0.0004). The PM2$ sp{+}$ allele (presence of a restriction site) was fixed in the fat line and occurred at a frequency of 63% in the lean line. Selection for ALV-resistance resulted in significant differences in the frequency of polymorphisms at PS1 and PM3. Selection for MD resistance also affected the frequency of polymorphisms at PS1 and PM3.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.60657
Date January 1992
CreatorsFotouhi Ardakani, Nasser, 1959-
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageMaster of Science (Department of Plant Science.)
RightsAll items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.
Relationalephsysno: 001287477, proquestno: AAIMM74493, Theses scanned by UMI/ProQuest.

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