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The relation of certain streptococcal products to the pathogenicity of group A streptococci in the hamster cheek pouch and in the mouse

Thesis (Ph.D.)--Boston University / The role of specific streptococcal products in the production of infection by these organisms has been the subject of many studies by previous investigators. To a great extent these workers have attempted to correlate the formation of these substances by certain streptococcal strains with their virulence and disease manifestations in man as well as with the lethal effects produced by these organisms in mice. The purpose of this study was to investigate further the role of individual streptococcal products in the pathogenicity of group A streptococci, mainly by observing the effects of these products on local and systemic infections in the hamster and the mouse, respectively. Specifically, the M protein, streptokinase, streptodornase, streptolysin 0, the erythrogenic toxin, the hyaluronic acid capsule, and hyaluronidase were studied. [TRUNCATED]

Identiferoai:union.ndltd.org:bu.edu/oai:open.bu.edu:2144/23928
Date January 1956
CreatorsKrasner, Robert Irving
PublisherBoston University
Source SetsBoston University
Languageen_US
Detected LanguageEnglish
TypeThesis/Dissertation
RightsBased on investigation of the BU Libraries' staff, this work is free of known copyright restrictions.

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