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Failure of Ceftolozane-Tazobactam Salvage Therapy in Complicated Pneumonia With Lung Abscess

Treatment of Pseudomonas aeruginosa remains challenging, despite the availability ceftolozane-tazobactam. We report a treatment failure with ceftolozane-tazobactam salvage therapy for pneumonia complicated by lung abscess. Drug resistance, dose selection, and source control are possible contributing factors. Ceftolozane-tazobactam susceptibility testing should precede therapy and consideration should be given to dosing selection.

Identiferoai:union.ndltd.org:ETSU/oai:dc.etsu.edu:etsu-works-11528
Date01 July 2018
CreatorsLewis, Paul O., Cluck, David B., Tharp, Jennifer L., Krolikowski, Matthew A., Patel, Paras D.
PublisherDigital Commons @ East Tennessee State University
Source SetsEast Tennessee State University
Detected LanguageEnglish
Typetext
SourceETSU Faculty Works

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