Digitized using a Konica Minolta 211 PCL Scanner. 300dpi (OCR). / Thesis (MA (Psychology))--University of Stellenbosch, 2007. / ENGLISH ABSTRACT: The first objective of the present study was to determine whether the Theory of
Planned Behaviour (TPB) could predict Willingness to Participate (WTP) in a future
Phase III HIV vaccine trial among high risk adolescents in the Western Cape. The
second objective was to determine whether the additional predictor variables of Self perceived
risk of HIV infection, Knowledge of HIV vaccines and HIV vaccine trials,
Attitudes toward HIV I AIDS and Health-promoting behaviours could further explain
WTP in a future Phase III HIV vaccine trial among adolescents. A convenience
sample of 224 adolescents attending secondary schools located in an African
township on the Cape Flats was recruited for the present study. Hierarchical logistic
regression analyses indicated that the TPB significantly improved the prediction of
WTP in an HIV vaccine trial. Prediction success was 79.9%. Of all the predictor
variables, only Subjective norms significantly predicted WTP in an HIV vaccine trial
(OR = 1.19,95% C.L = 1.06-1.34). A second stepwise logistic regression analysis
showed that Subjective norms (OR = 1.19, 95% c.I. = l.07-1.34) and Attitude
towards participation in an HIV vaccine trial (OR = 1.32,95% C.L = 1.00-1.74) were
significant predictors of WTP in an HIV vaccine trial. Prediction success was 80.4%.
These findings provide support for the Theory of Reasoned Action (TRA) and
suggest that psychosocial factors may play a role in WTP in a future Phase III HIV
vaccine trial among adolescents. HIV vaccine trial preparedness programs targeting
adolescents should aim to influence group norms positively and promote positive
attitudes toward participation in a future Phase III HIV vaccine trial. / AFRIKAANSE OPSOMMING: Die eerste oogmerk van die huidige studie was om te bepaal of die teorie van
beplande gedrag (TBG) die bereidwilligheid tot deelname (BTD) aan 'n toekomstige
fase III-MIV-entstofproefneming onder hoe risiko adolessente in die Wes-Kaap kan
voorspel. Die tweede oogmerk was om te bepaal of die bykomende
voorspellingveranderlikes, naamlik selfwaargenome risiko vir MIV -besmetting,
kennis van MIV -entstowwe en MIV -entstofproefnemings, houdings jeens MIV /Vigs
en gesondheidsbevorderende gedrag BTD in 'n toekomstige fase III-MIV entstofproefneming
kan verduidelik. 'n Geriefsmonster van 224 adolessente wat
sekondere skole gelee in 'n dorpsgebied in Kaapstad, bywoon, is vir die huidige
studie gewerf. Hierargiese logistiese regressie-analises toon dat die TBG die
voorspelling van BTD aan 'n MIV -entstofproefneming aanmerklik verbeter het.
Voorspellingsukses was 79.9%. Van al die voorspellingveranderlikes het slegs
subjektiewe norme BTD aan 'n MIV -entstofproefneming beduidend voorspel (RK =
1.19, 95% VI = 1.06-1.34). 'n Tweede stapsgewyse logistiese regressie-analise toon
dat subjektiewe norme (RK = 1.19, 95% VI = 1.07-1.34) en houding jeens deelname
aan 'n MIV-entstofproefneming (RK = 1.32,95% VI = 1.00-1.74) beduidende
voorspellers van BTD aan 'n MIV -entstofproefneming was. Voorspellingsukses was
80.4%. Hierdie bevindinge verleen steun aan die teorie van beredeneerde aksie (TBA)
en doen aan die hand dat psigososiale faktore moontlik in die toekoms 'n rol in BTD
aan 'n fase Ill-MIV-entstofproefneming onder adolessente kan speel. Programme wat
op adolessente se gereedheid vir entstofproefnemings afgestem is, behoort te poog om
groepnormne positief te beinvloed en positiewe houdings jeens deelname aan 'n
toekomstige fase III -MIV -entstofproefneming te bevorder.
| Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:sun/oai:scholar.sun.ac.za:10019.1/4868 |
| Date | 03 1900 |
| Creators | Giocos, Georgina |
| Contributors | Kagee, S. A., University of Stellenbosch. Faculty of Arts and Social Sciences. Dept. of Psychology, University of Stellenbosch. Faculty of Arts and Social Sciences. Dept. of Psychology. |
| Publisher | Stellenbosch : University of Stellenbosch |
| Source Sets | South African National ETD Portal |
| Language | en_ZA |
| Detected Language | English |
| Type | Thesis |
| Format | 96 p. : ill. |
| Rights | University of Stellenbosch |
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