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Serologically Documented Loracarbef (Lorabid)-Induced Immune Thrombocytopenia

We report here the first case of severe Immune thrombocytopenia induced by a secondgeneration cephalosporin antibiotic, Loracarbef. A 56-year old white female developed acute severe thrombocytopenia associated with acute respiratory symptoms following administration of Loracarbef. She responded to Loracarbef withdrawal and systemic corticosteroid administration. Loracarbef-dependent platelet-reactive antibodies were demonstrable in her serum by flow cytometry.

Identiferoai:union.ndltd.org:ETSU/oai:dc.etsu.edu:etsu-works-15269
Date01 May 2003
CreatorsAljitawi, O. S., Krishnan, K., Curtis, B. R., Bougie, D. W., Aster, R. H.
PublisherDigital Commons @ East Tennessee State University
Source SetsEast Tennessee State University
Detected LanguageEnglish
Typetext
SourceETSU Faculty Works

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