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Pluronic® block-copolymers in medicine: from chemical and biological versatility to rationalisation and clinical advances

Yes / This mini-review highlights the latest advances in the chemistry and biology of Pluronic® triblock copolymers. We focus on their applications in medicine, as drug delivery carriers, biological response modifiers, and pharmaceutical ingredients. Examples of drug delivery systems and formulations currently in clinical use, clinical trials or preclinical development are highlighted. We also discuss the role that Pluronic® copolymers may play in the innovative design of new nanomedicines in the near future. / We thank the Leverhulme Trust (Early Career Fellowship no. ECF-2013-414 to NPEB), the University of Warwick (Grant no. RDF 2013-14 to NPEB) and EPSRC (EP/G004897/1 to APB) for support.

Identiferoai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/11223
Date24 March 2014
CreatorsPitto-Barry, Anaïs, Barry, Nicolas P.E.
Source SetsBradford Scholars
LanguageEnglish
Detected LanguageEnglish
TypeArticle, Published version
Rights© 2014 The Royal Society of Chemistry. Reproduced in accordance with the publisher's self-archiving policy. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence., CC-BY

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