Espondilectomia parcial ventral cervical com osteotomia piezoelétrica e convencional em coelhos (Oryctolagus cuniculus) / Cervical ventral partial spondilectomy with piezoeletric and conventional osteotomy in rabbits (Oryctolagus cuniculus)

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Previous issue date: 2017-10-09 / A cirurgia piezoelétrica ou piezocirurgia é utilizada há várias décadas, porém em medicina veterinária são escassos os artigos publicados utilizando esta modalidade em cirurgias descompressivas da coluna vertebral de cães e gatos. Assim, aventou-se com esse trabalho investigar a aplicabilidade da mesma na realização da espondilectomia parcial ventral cervical (EPVC), comparando-a com a técnica convencional que utiliza brocas esféricas de alta rotação para o desgaste ósseo, utilizando o coelho (Oryctolagus cuniculus) como modelo experimental de cães e gatos. Para tanto foi utilizado o aparelho médico Mastersonic®, que possui duas peças de mão, uma piezoelétrica com ponteira ultrassônica tipo cinzel delicado (T1) e na outra, motor de alta rotação com brocas esférica de 2 mm (técnica convencional) (T2). A EPVC foi realizada entre a terceira e quarta vértebras cervicais e cada técnica foi realizada em 15 animais, devidamente anestesiados, os quais foram avaliados quanto à duração de cada etapa da cirurgia, variações de temperatura durante a execução da EPVC, visibilidade do campo cirúrgico, complicações trans e pós-operatórias e monitoração anestésica. Aos 14, 28 e 56 dias de pós-operatório (PO), cinco animais de cada tratamento foram submetidos à eutanásia e realizado estudo histopatológico do local da cirurgia, avaliando à resposta inflamatória, à cicatrização óssea e as lesões medulares. Os resultados mostraram que T1 demandou mais tempo para a execução da curetagem e maior perda de temperatura no foco cirúrgico durante a cirurgia. O tempo de acesso cirúrgico reduziu progressivamente em torno de 50% até o oitavo procedimento de cada tratamento (T1 e T2), e após isso se manteve com a mesma duração nos dois tratamentos. O tempo de uso do aparelho foi mais homogêneo em T1 e diminuiu progressivamente em T2, mas ao avaliar o tempo total da técnica de EPVC, não houve diferença entre os tratamentos. O T1 proporcionou melhor visibilidade do campo cirúrgico, com apenas um caso de sangramento ósseo, contra seis casos em T2. Observaram-se quatro casos de hemorragia de seio venoso vertebral durante a curetagem no T1 e dois casos no T2. Também ocorreram três casos de déficits proprioceptivos transitórios, com duração de até 72 horas no T1. A temperatura corporal e a taxa de uso do isoflurano decaíram com o tempo nos dois tratamentos, assim como a frequência cardíaca em T1. No estudo histopatológico observou-se resposta inflamatória mais ativa em T1 aos 14 dias de PO, porém aos 28 e 56 dias de PO foi semelhante entre os tratamentos, assim como a cicatrização óssea. Ainda houve mais lesões medulares com a piezocirurgia (T1), principalmente aos 14 e 28 dias de PO, com presença de malácia, esferócitos e células “Gitter”. Enquanto que na técnica convencional (T2), notou-se discreta degeneração Walleriana, apenas aos 14 dias de PO. Conclui-se que a piezocirurgia é aplicável na realização da EPVC com excelente visibilidade do campo operatório, facilidade de manuseio e rápida curva de aprendizagem, no entanto, demandou maior tempo para execução da espondilectomia e provocou mais complicações cirúrgicas e de lesões medulares, quando comparada à técnica convencional. / Piezoelectric surgery or piezosurgery has been used for several decades, but in veterinary medicine, articles published using this modality in decompressive surgery of the spine of dogs and cats are scarce. The aim of this study was to investigate the applicability of this technique to the performance of cervical ventral partial spondylectomy (CVPS), comparing it with the conventional technique using high-rotation spherical drills for bone wear using rabbit (Oryctolagus cuniculus) as an experimental model of dogs and cats.. For this was used Mastersonic® medical device that has two hand pieces, one piezoelectric type with ultrasonic delicate chisel tip (T1) and the other, high speed engine with spherical drills 2 mm (conventional technique) (T2). The CVPS was held between the third and fourth cervical vertebrae and each technique was performed on 15 animals, under anesthesia, which were evaluated for the duration of each stage of surgery, temperature variations during the execution of CVPS, the surgical field visibility, trans and postoperative complications and anesthetic monitoring. At 14, 28 and 56 postoperative days (PO), five animals per treatment were euthanized, and histological studies were carried to the surgical site by assessing the inflammatory response, and bone healing spinal injuries. The results showed that T1 required more time for curettage execution and highest loss of temperature at the surgical focus during surgery. Surgical access time progressively reduced by 50% until the eighth procedure of each treatment (T1 and T2), and after that it remained the same duration in both treatments. The time of use of the device was more homogeneous in T1 and progressively decreased in T2, but when evaluating the total time of the CVPS technique, there was no difference between treatments. The T1 provided better visibility of the surgical field, with only one case of bone bleeding, against six cases in T2. Four cases of vertebral venous sinus hemorrhage were seen during curettage in T1 and two cases in T2. There were also three cases of transient proprioceptive deficits, lasting up to 72 hours in T1. Body temperature and the rate of use of isoflurane declined over time in both treatments, as did heart rate in T1. Histopathological study there was more active inflammatory response in T1 at 14 days postoperatively, but after 28 and 56 days postoperatively was similar among treatments, as well as to bone healing. There were still more spinal cord injuries with the piezosurgery (T1), especially at 14 and 28 days of PO, with presence of malacia, spherocytes and Gitter cells. While the conventional technique (T2), it was noted discrete Wallerian degeneration, only at 14 days postoperatively. It is concluded that the piezosurgery is applicable in the performance of the CVPS with excellent visibility of the operative field, ease of handling and rapid learning curve, however, demanded more time for the execution of the spondylectomy and caused more surgical complications and spinal cord injuries, when compared to the conventional technique.

Links & Downloads

1. http://hdl.handle.net/11449/152285
2. 000895067
3. 33004102069P8

Tags

aparelho piezoelétrico

fenda ventral

piezocirurgia

neurocirurgia

piezoelectric device

ventral slot

piezosurgery

neurosurgery

Additional Fields

Identifer	oai:union.ndltd.org:IBICT/oai:repositorio.unesp.br:11449/152285
Date	09 October 2017
Creators	Roscamp, Marcelo
Contributors	Universidade Estadual Paulista (UNESP), Dias, Luis Gustavo Gosuen Gonçalves [UNESP]
Publisher	Universidade Estadual Paulista (UNESP)
Source Sets	IBICT Brazilian ETDs
Language	Portuguese
Detected Language	Portuguese
Type	info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis
Source	reponame:Repositório Institucional da UNESP, instname:Universidade Estadual Paulista, instacron:UNESP
Rights	info:eu-repo/semantics/openAccess
Relation	600, 600