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Cytotoxic Constituents from Soft Coral Clavularia viridis

Seven new steroids, GN70-153E (1), GN70-153F (2), GN70-153I (3), GN70-272F (4), GN70-272I (5), GN70-272L (6), and GN70-272L (7), were isolated from the Formosan soft coral Clavularia viridis by chromatographic separation of the EtOAc layer which was obstained from crude extraction in hexane¡ÐAcetone, 100% Acetone, Acetone¡ÐMeOH and 100% MeOH then partitioned between EtOAc and H2O. Their structures were determined based on the results of several kinds of spectroscopic analyses and HRESI-MS. Compounds 1-7 exhibited cyctotoxicity against HT-29 and P-388 cell lines in vitro.

Identiferoai:union.ndltd.org:NSYSU/oai:NSYSU:etd-0829106-135710
Date29 August 2006
CreatorsLo, I-wen
ContributorsJhy-Horng Sheu, Chang-Yih Duh, Wen Zhi-Hong
PublisherNSYSU
Source SetsNSYSU Electronic Thesis and Dissertation Archive
LanguageCholon
Detected LanguageEnglish
Typetext
Formatapplication/pdf
Sourcehttp://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0829106-135710
Rightscampus_withheld, Copyright information available at source archive

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