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Group-wise 3D MR Image Registration of Mouse Embryos

This dissertation provides the foundations of computer-based automated phenotyping methods for analyzing 3D images of mouse embryos. A group-wise registration technique was utilized and optimized and computerized methods were employed for analysis of 3D MRI images of mouse embryos.

The assumption that embryo anatomy is highly conserved among genetically identical specimens was verified. The group-wise registration approach was used to align a group of embryos from the 129S1/SvImJ (129Sv) strain as well as a group of C57BL/6J (C57) embryos.

Finally, we shed some light on some of the morphological differences between the 129Sv and C57 strains using automated techniques.

Identiferoai:union.ndltd.org:TORONTO/oai:tspace.library.utoronto.ca:1807/19329
Date15 March 2010
CreatorsZamyadi, Mojdeh
ContributorsSled, John G.
Source SetsUniversity of Toronto
Languageen_ca
Detected LanguageEnglish
TypeThesis

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