Two leaves of errata and addenda pasted into back pages. / Bibliography: leaves 174-208. / xix, 208 leaves : ill. ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis aimed to determine general roles for insulin-like growth factor binding proteins (IGFBPs) in regulating insulin-like growth factor-I (IGF-I) actions in wound repair. Preliminary experiments sought to characterise alterations to IGF-I levels and IGFBP profiles that may occur during wound repair. The effects that interactions with IGFBPs may have on IGF actions in wounds were addressed. Final experiments aimed to determine whether IGFBP-3 proteolysis observed in the initial work of the thesis acted to increase IGF bioavailablity. The results are discussed. / Thesis (Ph.D.)--University of Adelaide, Dept. of Surgery, 2000
| Identifer | oai:union.ndltd.org:ADTP/260963 |
| Date | January 1999 |
| Creators | Robertson, James Gray |
| Source Sets | Australiasian Digital Theses Program |
| Language | en_US |
| Detected Language | English |
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