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The Development of Amino Acid-Derived Catalysts for the Enantioselective Silylation of Alcohols: An Application to the Total Synthesis of Sapinofuranone A

Thesis advisor: Marc L. Snapper / Chapter 1. Review of efficient, non-enzymatic methods for the catalytic enantioselective functionalizations of alcohols Chapter 2. Introduction of the first catalytic asymmetric silylation of of alcohols for the desymmetrization of meso-diols Chapter 3. Presentation of enantioselective catalytic silylation for the regiodivergent reaction on a racemic mixture. Application of this method to the first enantioselective synthesis of sapinofuranone A. / Thesis (PhD) — Boston College, 2010. / Submitted to: Boston College. Graduate School of Arts and Sciences. / Discipline: Chemistry.

Identiferoai:union.ndltd.org:BOSTON/oai:dlib.bc.edu:bc-ir_101638
Date January 2010
CreatorsRodrigo, Jason
PublisherBoston College
Source SetsBoston College
LanguageEnglish
Detected LanguageEnglish
TypeText, thesis
Formatelectronic, application/pdf
RightsCopyright is held by the author, with all rights reserved, unless otherwise noted.

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