Yes / The creation of salts is a frequently used approach for the modification of physicochemical properties of an active pharmaceutical ingredient. Despite the frequency of application, there has been little research into the structural-property relationships of the final material and the nature of the counterion present. This work reports on five new salts of sulfathiazole and compares the energetics of the intermolecular interactions with variation in the crystal packing motifs.
| Identifer | oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/16328 |
| Date | 29 May 2018 |
| Creators | Seaton, Colin C., Rayan, R.T., Essifaow, E.A.A., Nauha, E., Munshi, Tasnim, Scowen, Ian J. |
| Source Sets | Bradford Scholars |
| Language | English |
| Detected Language | English |
| Type | Article, Accepted Manuscript |
| Rights | (c) 2018 Royal Society of Chemistry. Full-text reproduced in accordance with the publisher's self-archiving policy. |
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