Synthesis of citrate-ciprofloxacin conjugates.

Description

no / Two regioisomeric citrate-functionalized ciprofloxacin conjugates have been synthesized and their antimicrobial
activities against a panel of clinically-relevant bacteria have been determined. Cellular uptake
mechanisms were investigated using wild-type and ompF deletion strains of Escherichia coli K-12.

Links & Downloads

1. Md-Saleh, S. R., Chilvers, E. C., Kerr, K. G., Milner, S. J., Snelling, A. M., Weber, J. P., Thomas, G. H., Duhme-Klair, A-K. and Routledge, A. (2009). Synthesis of citrate-ciprofloxacin conjugates. Bioorganic & Medicinal Chemistry Letters. Vol. 19, pp. 1496-1498.
2. http://hdl.handle.net/10454/4843
3. https://doi.org/10.1016/j.bmcl.2009.01.007

Tags

Citrate-ciprofloxacin conjugates

Antimicrobial activity

Antibiotics

Ciprofloxacin

Synthesis

Additional Fields

Identifer	oai:union.ndltd.org:BRADFORD/oai:bradscholars.brad.ac.uk:10454/4843
Date	January 2009
Creators	Md-Saleh, S.R., Chilvers, E.C., Kerr, Kevin G., Milner, S.J., Snelling, Anna M., Weber, J.P., Thomas, G.H., Duhme-Klair, A-K., Routledge, A.
Source Sets	Bradford Scholars
Language	English
Detected Language	English
Type	Article, published version paper