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Comparison of muscle fiber type from normal and regenerated rat gastrocnemius through myosin ATPase staining

Regeneration of the gastrocnemius muscle in 25 white rats was reinvestigated using reimplantation of minced muscle fragments in order to compare the fiber profiles of the regenerate and normal contralateral gastrocnemius. Fiber profiles were prepared from both the regenerate and the normal muscle 45 days postoperatively using myosin ATPase histochemistry.Counts made of type 1, 2A, 2B, and 2C fibers showed a significant (P<(0.05) change in the profile of the regenerated muscle compared to the contralateral muscle.The results indicated that although there was a change in the fiber profile at 45 days, the regenerated muscle appeared to follow a path of developmental recapitulation. Changes in the fiber appeared to be related to reinnervation of the regenerate.Ball State UniversityMuncie, IN 47306

Identiferoai:union.ndltd.org:BSU/oai:cardinalscholar.bsu.edu:handle/182064
Date03 June 2011
CreatorsPearson, David Roy
ContributorsLesh, Thomas A.
Source SetsBall State University
Detected LanguageEnglish
Formativ, 53 leaves : ill. ; 28 cm.
SourceVirtual Press

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