High-throughput experiments have produced convicing evidence for an extensive
contribution of diverse classes of RNAs in the expression of genetic information.
Instead of a simple arrangement of mostly protein-coding genes, the human tran-
scriptome features a complex arrangement of overlapping transcripts, many of
which do not code for proteins at all, while others “sample” exons from several
different “genes”. The complexity of the transcriptome and the prevalence of non-
coding transcripts forces us to reconsider both the concept of the “gene” itself and
our understanding of the mechanisms that regulate “gene expression”.
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa:de:qucosa:32008 |
| Date | 24 October 2018 |
| Creators | Prohaska, Sonja J., Stadler, Peter F. |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, doc-type:conferenceObject, info:eu-repo/semantics/conferenceObject, doc-type:Text |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 978-981-281-232-2 |
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