Cognitive and affective dysfunctions are frequent but often neglected symptoms in Parkinson’s disease (PD). We developed the screening tool Parkinson neuropsychometric dementia assessment (PANDA) with five cognitive tasks and a short depression questionnaire. Healthy subjects and patients without cognitive impairment (PD), mild cognitive disorder (PD-MCD), or dementia (PDD) were examined. The cognition part had a specificity of 91% and a sensitivity of 90% for PDD and 77% for PDD plus PD-MCD patients. The mood questionnaire also had high sensitivity and specificity. We conclude that the PANDA is an economical, easy-to-use and sensitive tool to detect neuropsychological dysfunctions in PD patients in clinical practice.
| Identifer | oai:union.ndltd.org:DRESDEN/oai:qucosa.de:bsz:14-qucosa-110330 |
| Date | 10 April 2013 |
| Creators | Kalbe, Elke, Calabrese, Pasquale, Kohn, Nils, Hilker, Rüdiger, Riedel, Oliver, Wittchen, Hans-Ulrich, Dodel, Richard, Otto, Jörg, Ebersbach, Georg, Kessler, Josef |
| Contributors | Technische Universität Dresden, Fakultät Mathematik und Naturwissenschaften |
| Publisher | Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden |
| Source Sets | Hochschulschriftenserver (HSSS) der SLUB Dresden |
| Language | English |
| Detected Language | English |
| Type | doc-type:article |
| Format | application/pdf |
| Source | Parkinsonism & Related Disorders, Bd. 14 (2008), Nr. 2, S. 93–101, ISSN: 1353-8020 |
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