Submitted by Sandra Pereira (srpereira@ufrrj.br) on 2016-07-29T13:36:35Z
No. of bitstreams: 1
2011 - Bruno Rocha Pribul.pdf: 1463809 bytes, checksum: ba7b3b0f00c0b4469b45fe02ec9f8a7f (MD5) / Made available in DSpace on 2016-07-29T13:36:35Z (GMT). No. of bitstreams: 1
2011 - Bruno Rocha Pribul.pdf: 1463809 bytes, checksum: ba7b3b0f00c0b4469b45fe02ec9f8a7f (MD5)
Previous issue date: 2011-02-24 / Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico - CNPq / PRIBUL, Bruno Rocha. Evaluation of Vancomycin Resistance and Susceptibility Profile
Bacteriocins of staphylococci isolated from bovine mastitis in Southern State of Rio de
Janeiro. 41p Thesis (Master of Veterinary Science). Instituto de Veterin?ria, Departamento
de Parasitologia Animal, Universidade Federal Rural do Rio de Janeiro, Serop?dica, RJ, 2011.
Bacteria of the genus Staphylococcus are among the most implicated in the etiology of
mastitis. An additional difficulty in controlling bacterial infections by this genus is
represented by its frequent resistance to antibiotics. The glycopeptides (eg vancomycin)
appear as an alternative therapy because of the increasing strains of staphylococci resistant to
beta-lactams, which are the drugs of choice in these infections. Thus, glycopeptide resistance
represents a threat to the future of antimicrobial therapy in humans and animals. This study
aimed to evaluate the profile of vancomycin resistance pheno-genotypically in
Staphylococcus spp. milk samples from cows with mastitis. All 150 isolates (50 isolates of
Staphylococcus aureus, 50 isolates of Staphylococcus intermedius and 50 isolates of
Coagulase-negative Staphylococcus spp. (CNS) were evaluated using the tests of disk
diffusion, agar microdilution and detection of vanA e vanB genes. The antimicrobial
susceptibility test showed high resistance to beta-lactam antibiotics for all groups. In the disk
diffusion test, 24% of coagulase-positive isolates showed resistance to teicoplanin (24/100)
and 23% to vancomycin (23/100). In the agar microdilution test for detection of CIM, 16% of
the isolates were resistant to vancomycin (16/100). Among the resistant isolates in the agar
microdilution testing, 56.25% of the isolates (9 / 16) had MIC values ranging from 4-8?g/ml.
Staphylococcus coagulase-negative showed no resistance to the evaluated glycopeptides.
Genes for resistance to vancomycin were detected in 37.5% of vancomycin-resistant isolates
(6 / 16). To seek a correlation between the presence of glycopeptide resistance and the ability
of producing biofilm, tests were performed to characterize growth in Congo red agar and also
detection of the biofilm adherence test in microplates. It were detected 66.66% and 90, 00%,
respectively, of isolates producing biofilm. The production of "slime" presented no statistical
correlation with resistance to glycopeptides. The sensitivity profile of Staphylococcus spp.
was assessed against the bacteriocins produced by Lactobacillus paracasei, Lactobacillus
acidophilus and Lactobacillus fermentum. Lactobacillus paracasei bacteriocins presented the
highest inhibition capacity. / PRIBUL, Bruno Rocha. Avalia??o da Resist?ncia a Vancomicina e do Perfil de
Suscetibilidade a Bacteriocinas de Staphylococcus spp Isolados de Mastite Bovina da
Regi?o Sul do Estado do Rio de Janeiro. 41p Disserta??o (Mestrado em Ci?ncias
Veterin?rias). Instituto de Veterin?ria, Departamento de Parasitologia Animal, Universidade
Federal Rural do Rio de Janeiro, Serop?dica, RJ, 2011.
As bact?rias do g?nero Staphylococcus est?o entre as mais implicadas na etiologia das mastites. Uma
dificuldade adicional no controle das infec??es bacterianas por este g?nero ? representada por sua
freq?ente resist?ncia aos antimicrobianos. Os glicopept?deos, como a vancomicina, aparecem como
uma alternativa terap?utica devido ao crescente aumento de cepas estafiloc?cicas resistentes aos
betalact?micos, que s?o os f?rmacos de elei??o nestas infec??es. Desse modo, a resist?ncia aos
glicopept?deos representa uma amea?a ao futuro da terapia antimicrobiana em humanos e animais. O
presente trabalho buscou avaliar o perfil de resist?ncia ? vancomicina em isolados de Staphylococcus
spp. oriundos de amostras de leite de vacas com mastite. Todos os 150 isolados estudados (50
Staphylococcus aureus, 50 Staphylococcus intermedius e 50 Staphylococcus spp. coagulase
negativos), foram avaliados atrav?s dos testes de difus?o em disco simples, microdilui??o em ?gar e
detec??o dos genes vanA e B. O teste de suscetibilidade antimicrobiana revelou elevada resist?ncia aos
beta-lact?micos para todos os grupos avaliados. No ensaio de difus?o em disco, os isolados coagulasepositivos
apresentaram um perfil de resist?ncia de 24% a teicoplanina (24/100) e 23% a vancomicina
(23/100). No teste de microdilui??o em ?gar para detec??o da CIM, 16% dos isolados apresentaram
resist?ncia ? vancomicina (16/100). Entre os isolados resistentes no teste de microdilui??o em ?gar,
56,25% dos isolados (9/16) apresentaram valores de CIM que variaram entre 4-8?g/ml. Os
Staphylococcus coagulase-negativos n?o apresentaram resist?ncia aos glicopeptideos. Os genes de
resist?ncia ? vancomicina foram detectados em 37,5% dos isolados vancomicina-resistentes (6/16).
Para se buscar uma correla??o entre a presen?a de resist?ncia aos glicopeptideos e a capacidade de
forma??o de biofilme foram realizados os testes de caracteriza??o de crescimento em ?gar vermelho
congo e detec??o de biofilme pelo teste de ader?ncia em microplacas, onde foram detectados 66,66% e
90,00% respectivamente, de isolados produtores de biofilme. A produ??o de ?slime? n?o apresentou
correla??o estat?stica com a resist?ncia aos glicopept?deos. O perfil de sensibilidade dos isolados de
Staphylococcus spp. foi avaliado frente as bacteriocinas produzidas pelos Lactobacillus paracasei,
Lactobacillus acidophillus e Lactobacillus fermentum. As bacteriocinas que apresentaram maior
capacidade de inibi??o frente aos Saphylococcus spp. testados foram as produzidas pelos
Lactobacillus paracasei
| Identifer | oai:union.ndltd.org:IBICT/oai:localhost:jspui/1142 |
| Date | 24 February 2011 |
| Creators | Pribul, Bruno Rocha |
| Contributors | Souza, Miliane Moreira Soares de |
| Publisher | Universidade Federal Rural do Rio de Janeiro, Programa de P?s-Gradua??o em Ci?ncias Veterin?rias, UFRRJ, Brasil, Instituto de Veterin?ria |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis |
| Format | application/pdf |
| Source | reponame:Biblioteca Digital de Teses e Dissertações da UFRRJ, instname:Universidade Federal Rural do Rio de Janeiro, instacron:UFRRJ |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | 7. REFER?NCIAS BIBLIOGR?FICAS AARESTRUP, F.M. Occurrence of glycopeptide resistance among Enterococcus faecium isolates from conventional and ecological poultry farms. Microbiology Drug Resistance. v.1, p. 255?257, 1995. AARESTRUP, F.M.; BAGER, F.; JENSEN, N.E.; MADSEN, M.; MEYLING, A.; WEGENER, H.C. Resistance to antimicrobial agents used for animal therapy in pathogenic, zoonotic and indicator bacteria isolated from different food animals in Denmark: a baseline study for the Danish Integrated Antimicrobial Resistance Monitoring Programme (DANMAP). APMIS. v. 106, p. 745-770, 1998. AARESTRUP, F.M.; AGERSO, Y.; AHRENS, P.; JORGENSEN, J.C.O.; MADSEN, M.; JENSEN, L.B. Antimicrobial susceptibility and presence of resistance genes in staphilococci from poultry. Veterinary Microbiology. v. 74, p. 353-364, 2000. AARESTRUP, F.M.; SEYFARTH, A.M.; EMBORG, H.D.; PEDERSEN, K.; HENDRIKSEN, R.S.; BAGER, F. Effect of abolishment of the use of antimicrobial agents for growth promotion on occurrence of antimicrobial resistance in fecal enterococci from food animals in Denmark. Antimicrobial Agents Chemoter. v.45, p. 2054? 2059, 2001. ABADIA, P.L.; COURVALIN, P.; PERICHON, B. vanE gene cluster of vancomycinresistant Enterococcus faecalis BM4405. Journal of Bacteriology. v.184, p. 6457?6464, 2002. AGUILAR, B.; AMORENA, B.; ITURRALDE, M. Effect of slime on adherence of Staphylococcus aureus isolated from bovine and ovine mastitis. Veterinary Microbiology. v.78, p.183-191, 2001. AKINEDEN, ?.; ANNEM?LLER, C.; HASSAN, A.A.; L?MMLER, C.; WOLTER, W.; ZSCH?CK, M. Toxin genes and other characteristics of Staphylococcus aureus isolates from milk of cows with mastitis. Clinical Diagn?stic Laborat Immunol. v.8, p. 959-964, 2001. AMORENA, B.; BASELGA, R.; AGUILAR, B. Factors infuencing the degree of in vitro bacterial adhesion to ovine mammary gland epithelial cells. Veterinary Microbiology. v.24 p.43-53, 1999. ARCIOLA, C.R.; BALDASSARI, L.; MONTANARO, L. Presence of icaA and icaD and slime production in a collection of staphylococcal strains from catheter-associated infections. Journal Clinical Microbioloogy. v. 39, p. 2151-2156, 2001. ARTHUR, M.; MOLINAS, C.; DEPARDIEU, F.; COURVALIN, P. Characterization of Tn1546, a Tn3-related transposon conferring glycopeptide resistance by synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147. Journal of Bacteriology. v.175, p.117?127, 1993. ARTHUR, M.; DEPARDIEU, F.; MOLINAS, C.; REYNOLDS, P.; COURVALIN, P. The vanZ gene of Tn1546 from Enterococcus faecium BM 4147 confers resistance to teicoplanin. Gene. v.154, p.87?92, 1995. 46 ARTHUR, M.; REYNOLDS, P.; COURVALIN, P. Glycopeptide resistance in enterococci. Trends Microbiology. v.4, p.401?407, 1996. ARTHUR, M.; DEPARDIEU, F.; REYNOLDS, P.; COURVALIN, P. Quantitative analysis of the metabolism of soluble cytoplasm peptydoglican precursors of glycopeptides-resistant enterococci. Molecular Microbiology. v.21, p.33-44, 1996. AXELSSON, L.T. Lactic acid bacteria: classification and physiology. In: SALMINEN, S., VON WRIGHT, A. Lactic acid bacteria. New York: Marcel Dekker, 1993. p.1-63. BAIOCCHI, S.A.; TOGNIM, M.C.B.; BAIOCCHI, O.C.G.; SADER, H.S. Endocarditis due to glycopeptide-intermediate Staphylococcus aureus: case report and strain characterization. Diagn?stic Microbiology Infection Disease. v.45, p.149-152, 2003. BANNERMAN, T.L. Staphylococcus, Micrococcus, other catalasepositive cocci that grow aerobically. In: MURRAY, P.R.; BARON, E.J.; JORGENSEN, J.H.; PFALLER, M.A.; YOLKEN, R.H. Manual of Clinical Microbiology. Wasington: ASM Press, 2003. p. 384? 404. BARBERIS, L.; P?JARO, M.; ALBESA, I. In vitro inhibition of Gardnella vaginalis growth by bacteriocin produced by Lactobacillus strains. Revista Latino Americana de Microbiologia. v. 36, p.101-106, 1994. BARRASA, J.L.; GOMEZ, P.L.; LAMA, Z.G. Antibacterial susceptibility patterns of strains isolated from chronic canine otitis externa. Jornal Medicina Veterin?ria. v.47, p.191- 196, 2000. BASELGA, R.; ALBIZU, I.; DE LA CRUZ, M.; DEL CACHO, E.; BARBERAN, M.; AMORENA, B. Phase variation of slime production in Staphylococcus aureus implications in colonization and virulence. Infection Immunology. v.61, p.4857-4862, 1993. BEVERIDGE, T.J.; MAKIN, S.A.; KADURUGAMUWA, J.L.; LI, Z. Interactions between biofilms and the environment. FEMS Microbiology Review. v.20, p.291-303, 1997. BONNA, I.C.F.; SANTOS, A.P.V.; TEIXEIRA, G.N.; MOTTA, O.V. Staphylococcus coagulase-negativos resistentes a drogas isolados de leite de b?falas ( Bubalus Bubalis) Drug resistant coagulase-negative Staphylococci isolated from milk of buffaloes (Bubalus Bubalis). Revista Brasileira de Ci?ncias Veterin?rias. v.14, n.2, p.117-121, 2007. BRITO, J. R. F.; BRITO, M. A. V. P. Programas de controle das mastites causadas por microorganismos contagiosos e do ambiente. EMBRAPA-CNPGL. Juiz de Fora, 1998. BRITO, M.A.V.P.; BRITO, J.R.F.; SILVA, M.A.S.; CARMO, R.A. Concentra??o m?nima inibit?ria de dez antimicrobianos para amostras de S. aureus isoladas de infec??o intramam?ria bovina. Arquivo Brasileiro de Medicina Veterin?rio e Zootecnia. v.53, n.5, p.10-17, 2001. BROWN, M.R.; ALLISON, D.G.; GILBERT, P. Resistance of bacterial biofilms to antibiotics, a growth-rate related effect? Journal Antimicrobial Chemotherapy. v. 22, p. 777-780, 1988. 47 BRUNO, M.E.C.; MONTVILLE, T.J. Common mechanistic action of bacteriocins from lactic acid bacteria. Applied and Environmental Microbiology. v.59, n.9, p.3003-3010, 1994. BUZZOLA, F.R.; QUELLE, L.; GOMEZ, M.I.; CATALANO, M.; STEELE-MOORE, L.; BERG, D.; GENTILINI, E.; DENAMIEL, G.; SORDELLI, D.O. Genotypic analysis of Staphylococcus aureus from milk of dairy cows with mastitis in Argentina. Epidemiology Infection. v.126, p.445-452, 2001. BYARUGABA, D.K. A view on antimicrobial resistance in developing countries and responsible risk factors. International Journal Antimicrobial Agents. v.24, p.105-110, 2004. CAMPOS, M. M. C. Avalia??o de mastite bovina enfocando o Calif?rnia Mastitis Test, diagn?stico microbiol?gico sensibilidade in vitro. Cear?, Universidade Federal do Cear?, 2000. 105p. CARIAS, L.L.; RUDIN, S.D.; DONSKEY, C.J.; RICE, L,B. Genetic linkage and cotransfer of a novel, vanB-containing transposon (Tn5382) and a lowaffinity penicillin-binding protein 5 gene in a clinical vancomycin resistant Enterococcus faecium isolate. Journal of Bacteriology. v.180, p.4426?4434, 1998. CARMELI, Y.; ELIOPOULOS, G.M.; SAMORE, M.H. Antecedent Treatment with Different Antibiotic Agents as a Risk Factor for Vancomycin-Resistant Enterococcus. Emergency Infeciont Disease. v.8, p. 134-137, 2002. CARMINATI, D.; GIRAFFA, G.; BOSSI, M.G. Bacteriocin-like inhibitors of Streptococcus lactis against Listeria monocytogenes. Journal of Food Protection. v.52, n.9, p.614-617, 1989. CARVALHO, L.A. Embrapa gado de leite: sistema de produ??o. Dispon?vel na internet. www.cnpgl.embrapa.br/sistema/cerrado.htmL. Acesso em 16 set. 2009. CASEY, A.L.; LAMBERT, P.A.; ELLIOTT, T.S.J. Staphylococci. International Journal Antimicrobial Agents, Amsterdam. v. 29, p. 23-32, 2007. CASSETTARI, V.C.; STRABELLI, T.; MEDEIROS, E.A.S. Staphylococcus aureus bacteremia: what is the impact of oxacillin resistance on mortality? Brazilian Journal of Infecty Disease. v. 9, n. l, p. 70-6, 2005. CENTERS FOR DISEASE CONTROL AND PREVENTION. Staphylococcus aureus resistant to vancomycin?United States, 2 Morb Mortal Wkly Rep. v. 51, p. 565-567, 2002. CEREDA, R.F. Avalia??o do perfil de sensibilidade e caracteriza??o molecular de Enterococcus spp. Isolados em hospitais da Am?rica latina. Tese de Doutorado. Universidade Federal de S?o Paulo ? Escola Paulista de Medicina 1999. S?o Paulo/SP. CETINKAYA, Y.; FALK, P.; MAYHALL, C.G. Vancomycin-resistant enterococci. Clinical of Microbiology Reviews. v.13, p.686?707, 2000. 48 CHADWICK, P.R.; WOODFORD, N.; KACZMARSKI, E.B.; GRAY, S.; BARRELL, R.A.; OPPENHEIM, B.A. Glycopeptide-resistant enterococci isolated from uncooked meat. Journal of Antimicrobial Chemotherapy. v. 38, p. 908-909, 1996. CHAMBERS, H.F. Methicillin resistance in staphylococci: molecular and biochemical basis and clinical implications. Clinical Microbiology Revist. v.10, n.4, p.781-791, 1997. CHANG, S.; SIEVERT, D.M.; HAGEMAN, J.C.; BOULTON, M.L.; TENOVER, F.C.; DOWNES, F.P.; SHAH, S.; RUDRIK, J.T.; PUPP, G.R.; BROWN, W.J.; CARDO, D.; FRIDKIN, S.K. Infection with vancomycin-resistant Staphylococcus aureus containing the vanA resistance gene. New England Journal of Medicine. v.348, p. 1342-1347, 2003. CHAVERS, L.S.; MOSER, S.A.; BENJAMIN, W.H.; BANKS, S.E.; STEINHAUER, J.R.; SMITH, A.M.; JOHNSON, C.N. Vancomycin-resistant enterococci: 15 years and counting. Journal of Hospital Infection. v.53, p159-171, 2003. CHEN, Y.; LUDESCHER, R.D.; MONTVILLE, T.J. Electrostatic interactions, but not the YGNGV consensus motif, govern the biding of pediocin PA-1 and its fragments to phospholipid vesicles. Applied and Environmental Microbiology. v.63, n.12, p.4770-4777, 1997. CHIEW, Y.F.; HALL, M.C. Comparision of three methods for the molecular typing of Singapure isolates of enterococci with high-level aminoglycosides resistances. Journal of Hospital Infection. v.38, p.223-230, 1998. CHRISTENSEN, G.D.; SIMPSON, W.A.; YOUNGER, J.J.; BADDOUR, L.M.; BARRETT, F.F.; MELTON, D.M.; BEACHEY, E.H. Adherence of coagulasenegative staphylococci to plastic tissue culture plates: a quantitative model for the adherence of staphylococci to medical devices. Journal of Clinical Microbiology. v.22, p.996?1006, 1985. CILANO, L.; ROSSO, D.; BOSSO, M.G. Azione di sostanze inibitrici prodotte da batteri lattici verso microrganismi patogeni. L'Industria del Latte. v.27, n.3-4, p.3-20, 1991. CLINICAL AND LABORATORY STANDARDS INSTITUTE; Performance standards for antimicrobial disk susceptibility tests. Approved standards. CLSI document M2-A3. Clinical and Laboratory Standards Institute, Wayne, Pa, 2006. CLINICAL AND LABORATORY STANDARDS INSTITUTE; Performance standards for antimicrobial disk susceptibility tests. Approved standards. CLSI document M2-A3. Clinical and Laboratory Standards Institute, Wayne, Pa, 2010. CLEVELAND, J.; MONTVILLE, T.J.; NES, I.E.; CHIKINAS, M.L. Bacteriocins: safe, natural antimicrobials for food preservation. International Journal of Food Microbiology. v.71, p.1-20, 2001. COELHO, S.M.O.; MENEZES, R.A.; SOARES, L.C.; PEREIRA, I.A.; GOMES, L.P.; SOUZA, M.M.S. Mapeamento do Perfil de Resist?ncia e Detec??o do gene mecA em Staphylococcus aureus e Staphylococcus intermedius oxacilina-resistentes isolados de esp?cies humanas e animais. Ci?ncia Rural. v.37, n.1, p.195-200, 2007. 49 CONLEY, J.; OLSON, M.E.; COOK, L.S.; CERI, H.; PHAN, V.; DAVIES, H.D. Biofilm formation by group A streptococci: is there a relationship with treatment failure? Journal of Clinical Microbiology. v.41, p.4043-4048, 2003. COSGROVE, S.E.; CARROLL, K.C.; PERL, T.M. Staphylococcus aureus with reduced susceptibility to vancomycin. Clinical Infection Disease. v.39, p.539-45, 2004. COSTA, E.O. Import?ncia da mastite na produ??o leiteira do Brasil. Revista de Educa??o Continuada do CRMV-SP. v. 1, p. 3-9, 1998. COSTA, E.O.; BENITIS, N.R.; GUERRA, J.L.; GUERRA, J.L.; MELVILLE, P.A. Antimicrobial susceptibility of Staphylococcus spp. Isolated from mammary parenchymas of slaughtered dairy cows. Journal of Veterinary Medicine. v.47, p.99-103, 2000. CONTRERAS, G.A.; G?MEZ, C.A.; LEAL, A.L.; GONZ?LEZ, M.J.P.; NAVARRETE, M.L. Staphylococcus aureus resistente a la vancomicina: una nueva amenaza. Infectiology. v.9, n.2, p.91-99, 2005. COURVALIN, P. Vancomycin resistance in gram-positive cocci. Clinical Infection Disease. v.42(Suppl. 1), p.S25-S34, 2006. CRAMTON, S.E.; GERKE, C.; SCHNELL, N.F.; NICHOLS, W.W.; G?TZ, F. The intercellular adhesion (ica) locus is present in Staphylococcus aureus and is required for biofilm formation. Infection Immunology. v.67, p.5427-5433, 1999. CRUPPER, S.S.; IANDOLO, J.J. Purification and partial characterization of a novel antibacterial agent (Bac1829) produced by Staphylococcus aureus KSI1829. Applied and Environmental Microbiology. v.62, p.3171-3175, 1996. CUCARELLA, C.; SOLANO, C.; VALLE, J.; AMORENA, B.; LASA, I.; PENAD?S, J.R. Bap, a Staphylococcus aureus surface protein involved in biofilme formation. Journal of Bacteriology. v.183, p.2888-2896, 2001. CUI, L.; MURAKAMI, H.; KUWAHARA-ARAI, K.; HANAKI, H.; HIRAMATSU, K. Contribution of a thickened cell wall and its glutamine nonamidated component to the vancomycin resistance expressed by Staphylococcus aureus Mu50. Antimicrobial Agents Chemotherapy. v.44, n.9, p.2276-2285, 2000. CUI, L.; MA, X.; SATO, K.; OKUMA, K.; TENOVER, F.C.; MAMIZUKA, E.M. Cell wall thickening is a common feature of vancomycin resistance in Staphylococcus aureus. Journal of Clinical Microbiology. v.41, n.1, p.5-14, 2003. CUI, L.; IWAMOTO, A.; LIAN, J. Q.; NEOH, H.; MARUYAMA, T.; HORIKAWA, Y.; HIRAMATSU, K. Novel mechanism of antibiotic resistance originating in vancomycinintermediate Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. v.50, n.2, p.428-438, 2006. 50 DANTAS, M.D., ANDR?, P.B., SANTOS, P.P., CAMPOS, M.R.H., BORGES, L.J., SERAFINI, A.B. Utiliza??o do Antibiograma como Ferramenta de Tipagem Fenot?pica de Staphylococcus aureus Isolados de Manipuladores , Leite Cru e Queijo Minas Frescal em Latic?nio de Goi?s, Brasil Braz. Journal Veterinary Research of Animal Science. v. 43, suplemento, p. 102-108, 2006. DAVEY, G.P. Mode of action of diplococcin, a bacteriocin from Streptococcus cremoris 346. New Zealand Journal of Dairy Science and Technology. v.16, n.2, p.187-190, 1981. DE ARA?JO, G.L.; COELHO, L.R.; DE CARVALHO, C.B.; MACIEL, R.M.; CORONADO, A.Z.; ROZENBAUM, R.; FERREIRA-CARVALHO, B.T.; FIGUEIREDO, A.M.; TEIXEIRA, L.A. Commensal isolates of methicillin-resistant Staphylococcus epidermidis are also well equipped to produce biofilm on polystyrene surfaces. Journal of Antimicrobial Chemother.v. 57, p. 855-864, 2006. DE VUYST, L.; VANDAMME, E.J. Bacteriocins of Lactic Acid Bacteria: Microbiology, Genetics and Applications. London : Blackie Academic and Professional, 1994. DE WEERT, S.H.; VERMEIREN, I.H.; MULDERS, I.; KUIPER, N.; HENDRICKX, G.V.; BLOEMBERG, J.; VANDERLEYDEN, R.; DE MOT, Y.B.; LUGTENBERG, J. Flagelladriven chemotaxis towards exudates components is an important trait for tomato root colonization by Pseudomonas fluorescens. Molecular Plant-Microbe Interaction. v.15, p.1173-1180, 2002. DEPARDIEU, F.; REYNOLDS, P.E.; COURVALIN, P. VanD-type vancomycin-resistant Enterococcus faecium 10/96A. Antimicrobial Agents Chemotherapy. v.47, p.7?18, 2003. DEPARDIEU, F.; COURVALIN, P.; MSADEK, T. A six amino acid deletion, partially overlapping the VanSB G2 ATP-binding motif, leads to constitutive glycopeptide resistance in VanB-type Enterococcus faecium. Molecular Microbiology. v.50, p.1069?1083, 2003. DONLAN, R.M.; COSTERTON, J.W. Biofilms; survival mechanisms of clinically relevant microorganisms. Clinical of Microbiology Reviews. v.15, n.2, p.167-193, 2002. DONNELLY, J.P.; VOSS, A.; WITTE, W.; MURRAY, B.E. Does the use in animals of antimicrobial agents, including glycopeptide antibiotics, influence the efficacy of antimicrobial therapy in humans? Journal of Antimicrobial Chemotherapy. v. 37, p. 389- 390, 1996. EDMOND, M.B. Multidrug-resistant enterococci and the threat of vancomycin resistant Sthaphylococcus aureus. In: WENZEL, R.P. Prevention and control of nosocomial infections. 3 ed, Baltimore: Williams and Wilkins, 1997. p. 339-55. EIJSINK, V.G.H.; BRURBERG, M.B.; MIDDELLHOVEN, P.H.; NES, I.F. Induction of bacteriocin production in Lactobacillus sake by a secreted peptide. Journal of Bacteriology. v.178, n.8, p.2232-2237, 1996. ERSKINE, R.J.; EBERHART, R.J. Herd benefit-to-cost ratio and effects of a bovine mastitis control program that includes blitz treatment of Streptococcus agalactiae. Journal of the American Veterinary Medical Association. v. 196, n. 8, p.1230?1235, 1990. 51 ERSKINE, R.J.; WALKER, R.D.; BOLIN, C.A.; BARTLETT, P.C.; WHITE, D.G. Trends in antibacterial susceptibility of mastitis pathogens during a seven-year period. Journal of Dairy Science. v.85, p.1111?1118, 2004. EUZ?BY, J.P. List of prokaryotic names with standing in nomenclature ? Genus Staphylococcus, Toulouse 2007. Dispon?vel em: <http://www.bacterio.cict.fr/s/staphylococcus.htmL>. Acesso em: 10 nov. 2010. FACKLAM, R.R.; CARVALHO, M.G.; TEIXEIRA, L. History, taxonomy, biochemical characteristics, and antibiotic susceptibility testing of enterococci. In: GILMORE, M.S. The enterocossi-pathogenesis, molecular biology, and antibiotic resistance. Washington: ASM Press, 2002. p.1-54. FAGUNDES, H.; OLIVEIRA, C.A.F. Infec??es intramam?rias causadas por Staphylococcus aureus e suas implica??es em sa?de p?blica. Ci?ncia Rural. v.34, n.4, p.1315-1320, 2004. FARIAS, M.F. Terap?utica otol?gica. In: Manual de terap?utica veterin?ria. 2.ed. S?o Paulo: Roca, 2002. p.13-17. FARNWORTH, E.R. Probiotics and prebiotics. In: WILDMAN, R.E.C. Handbook of Nutraceutical and functional foods. 2a ed. London: CRC Press., 2001. p. 407 ? 422. FERREIRA, R.B.R.; NUNES, A.P.F.; KOKIS, V.M.; KREPSKY, N.; FONSECA, L.S.; BASTOS, M.C.F.; GIAMBIAGI-DEMARVAL, M.; SANTOS, K.R.N. Simultaneous detection of the mecA and ileS-2 genes in coagulase-negative staphylococci isolated from Brazilian hospitals by multiplex PCR. Diagnostic Microbiology Infectious Disease. v.42, p.205-212, 2002. FIGUEIREDO, J.B. Mamite bovina: vis?o panor?mica de uma doen?a complexa. Anais do Congresso Brasileiro de Produ??o Animal. v.11, p.176-194, 1995. FLOREY, H.W. The use of microorganisms for therapeutic purposes. Yale Journal Biology Medicine. v. 19, p.101-117, 1946. FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS, WORLD HEALTH ORGANIZATION. Evaluation of health and nutricional properties of probiotics in food including powder milk with live lactic acid bacteria. C?rdoba, 2001. 34p. FONSECA, L.F.L.; SANTOS, M.V. Qualidade do leite e controle de mastite. S?o Paulo: Lemos Editorial, 2000. FONSECA, D.A.C. (2005). Disserta??o de mestrado. Staphylococcus aureus resistentes a Oxacilina em Montes Claros ? MG: Caracteriza??o Microbiol?gica e Epidemiol?gica. Universidade Federal de S?o Paulo/Escola Paulista de Medicina. FOURICHON, C.; BEAUDEAU, F.; BAREILLE, N.; SEEGER, H. Incidence of health disorders in dairy farming systems in Western France. Livestock Production Science. v.68, p.157-170, 2001. 52 FRANZ, C.M.; HOLZAPFEL, W.H.; STILES, M.E. Enterococci at the crossroads of food safety? International Journal of Food Microbiology. v. 47, p. 1?24, 1999. FREEMAN, D. J. FALKINER, F.R.; KEANE, C. T. New method for detecting slime production by coagulase negative staphylococci. Joural Clinical Pathology, v. 42, p. 872- 874, 1989. FREITAS, M.F.L.; PINHEIRO J?NIOR, J.W.; STAMFORD, T.L.M.; RABELO, S.S.A.; SILVA, D.R.; SILVEIRA FILHO, V.M.; SANTOS, F.G.B.; SENA, M.J.; MOTA, R.A. Perfil de sensibilidade antimicrobiana in vitro de Staphylococcus coagulase positivos isolados de leite de vacas com mastite no agreste do estado de Pernambuco. Arquivo do Instituto de Biologia de S?o Paulo. v.72, p.171-177, 2005. FULLER, R. Probiotics: The Scientific Basis. Nova York:Chapman & Hall, 1992. GARNIER, F.; TAOURIT, S.; GLASER, P.; COURVALIN, P.; GALIMAND, M. Characterization of transposon Tn1549, conferring VanB-type resistance in Enterococcus spp. Microbiology. v.146, p.1481?1489, 2000. GARRITY, G. H.; HOLT, J. G. Taxonomic outline of the Archaea and Bacteria. In: GARRITY, G. H. Bergey?s Manual of Systematic Bacteriology. 2 ed. Nova York:Springer- Verlag, 2001. p. 427-446. GENTILINI, E.; DENAMIEL, G.; LLORENTE, P.; GODALY, S.; REBUELTO, M.; DEGREGORIO, O. Antimicrobial susceptibility of Staphylococcus aureus isolated from bovine mastitis in Argentina. Journal of Dairy Science. v. 83, p. 1224-1227, 2000. GOLAN, D.E.; ARMSTRONG, A.W.; ARMSTRONG, E.J.; TASHJIAN, A.H. Princ?pios de farmacologia: A Base Fisiopatol?gica da Farmacoterapia. 2? Ed, Boston:Nova Guanabara, 2009. G?TZ, F. Staphylococcus and biofilms. Molecular Microbiology. v.43, p.1367-1378, 2002. GRATIA, A. Sur un remarcable example d'antaginism entre deux souches de colibacille. C. R. Seances Society Biology Film. v. 93, p. 1040-1041, 1925. GRINHOLC, M.; WEGRZYN, G.; KURLENDA, J. Evaluation of biofilm production and prevalence of the icaD gene in methicillin-resistant and methicillin-susceptible Staphylococcus aureus strains isolated from patients with nosocomial infections and carriers. FEMS Immunology of Medical Microbiology. v. 50, p. 375-379, 2007. HANAKI, H.; LABISCHINSKI, H.; SASAKI, K.; KUWAHARA-ARAI, K.; INABA, Y.; HIRAMATSU, K. Mechanism of vancomycin resistance in MRSA strain Mu50. Japanese Journal of Antibiotics. v.51, n.3, p.237-247, 1998. HANCOCK, R. E. Cationic peptide: effectors in innate immunity and novel antimicrobials. Lancet Infection Disease. v. 1, p. 156-164, 2001. 53 HARRIS, L.J.; DAESCHEL, M.A.; KLAENHAMMER, T.D. Antimicrobial activity of lactic acid bacteria against Listeria monocytogenes. Journal of Food Protection. v.52, n.6, p.384- 387, 1989. HENG, N.C.K.; WESCOMBE, P.A.; BURTON, J.P.; JACK, R.W.; TAGG, J.R. The diversity of bacteriocins in Gram positive bacteria. In: RILEY, M.A.; CHAVAN, M.A. Bacteriocins: ecology and evolution. New York: Springer, 2007. p. 45-83. HIRAMATSU, K.; HANAKI, H.; INO, T.; YABUTA, K.; OGURI, T.; TENOVER, F.C. Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility. Journal of Antimicrobial Chemotherapy. v.40, p.135-146, 1997. HIRAMATSU, K.; ARITAKA, N.; HANAKI, H.; KAWASAKI, S.; HOSODA, Y.; HORI, S. Dissemination in Japanese hospitals of strains of Staphylococcus aureus heterogeneously resistant to vancomycin. Lancet. v.350, p.1670-1673, 1997. HIRAMATSU, K. Vancomycin resistance in staphylococci. Drug Resistance Updates. v. 1, p. 135-150, 1998. HIRAMATSU, K. Activated cell-wall synthesis is associated with vancomycin resistance in methicillin-resistant Staphylococcus aureus clinical strains Mu3 and Mu50. Journal of Antimicrobial Chemotherapy. v. 42, p.199-209, 1998. HIRAMATSU, K. Vancomycin-resistant Staphylococcus aureus: a new model of antibiotic resistance. The Lancet Infectious Diseases. v.1, p.147-155, 2001. HUGAS, M. Bacteriocinogenic lactic acid bacteria for the biopreservation of meat and meat products. Meat Scienci. v.49, p.1537-1542, 1998. JACK, R.W.; TAGG, J.R.; RAY, B. Bacteriocins of gram-positive bacteria. Microbiol. Molecular Biology Reviews. v.59, p.171-200, 1995. JOHN, M.A.; PLETCH, C.; HUSSAIN, S. In vitro activity of quinupristin/dalfopristin, linezolid, telitromycin and comparator antimicrobial agents against 13 species of coagulasenegative staphylococci. Journal of Antimicrobial Chemotherapy. v. 50, p. 933-938, 2002. JONG, S.K.; GONG, S.K.; CHUNG, H.K.; DAE, S.H. Dairy-cattle health in Gyeongnam, Korea. Preventive Veterinary Medicine. v.52, pp. 163-169, 2001. KAISER, A.L.; MONTVILLE, T.J. The influence of PH and growth rate on production of the bacteriocin, bavaricin MN, in batch and continuous fermentations. Journal of applied Microbiology. v.75, p.536-540, 1996. KATAYAMA, Y.; ITO, T.; HIRAMATSU, K. Genetic organization of the chromosome region surrounding mecA in clinical staphylococcal strains: role of IS431-mediated mecI deletion in expression of resistance in mecA-carrrying, low-level methicillinresistant Staphylococcus haemolyticus. Antimicrobial Agents and Chemotherapy. v.45, n.7, p.1955- 1963, 2001. 54 KIM, M.N.; PAI, C.H.; WOO, J.H.; RYU, J.S.; HIRAMATSU, K. Vancomycin-Intermediate Staphylococcus aureus in Korea. Journal of Clinical Microbiology. v.38, n.10, p.3879-3881, 2000. KIRK, M.; HILL, R.L.; CASEWELL, M.W.; BEIGHTON, D. Isolation of vancomycinresistant enterococci from supermarket poultry. Advances in Experimental Medicine and Biology. v. 418, p. 289?291, 1997. KLARE, I.; HEIER, H.; CLAUS, H.; B?HME, G.; MARIN, S.; SEITMANN, G.; ATANASSOVA, V.; WITTE, W. Enterococcus faecium strains with vanA-mediated highlevel glycopeptide resistance isolated from animal foodstuffs and faecal samples of humans in the community. Microbiology Drug Resistance. v. 1, p. 265-272, 1995. KLARE, I.; HEIER, H.; CLAUS, H.; REISSBRODT, R.; WITTE, W. vanA-mediated highlevel glycopeptide resistance in Enterococcus faecium from animal husbandry. FEMS Microbiology Letters. v.125, p.165-172, 1995. KLEIN, G.; PACK, A.; REUTER, G. Antibiotic resistance patterns of enterococci and occurrence of vancomycin-resistant enterococci in raw minced beef and pork in Germany. Applied and Environment Microbiology. v.64, p.1825?1830, 1998. KLOOS, W.E.; BANNERMAN, T.L. Staphylococcus and Micrococcus. In: MURRAY, P.A.; BARON, E.J.; PFALLER, M.A.; TENOVER, F.C.; YOLKEN, R.H. Manual of clinical microbiology. 7?ed. Washington: ASM Press, 1999. p.264-277. KOHNER, J .P.; UHL, J.; KOLBERT, C.; PERSING, D.; COCKERILL,F. A comparison of susceptibility testing methods with mecA Gene analysis for determining oxacilin (methicilin) resistance in clinical isolates of Staphylococcus aureus and coagulase negative Staphylococcus spp. Journal of Clinical Microbiology. v.37, n.9, p.2952-2961, 1999. KOJIC, M.; SVIRCEVIC, J.; BANINA, A.L; TOPISIROVIC, K. Bacteriocin producing strain of Lactococcus lactis subsp. diacetylactis S50. Applied and Environmental Microbiology. v.57, n.6, p.1835-1837, 1991. KONEMAM, E.W.; ALLEN, S.D.; JANDA, W.M; SCHRECKENBERGER, P.C.; WINN, J.R. Diagn?stico Microbiol?gico. 6.ed. Rio de Janeiro: Editora MEDS, 2008. KRUSE, H.; JOHANSEN, B.K.; R?RVIK, L.M.; SCHALLER, G. The. use of avoparcin as a growth promoter and the occurrence of vancomycin-resistant Enterococcus species in Norwegian poul-try and swine production. Microbiology Drug Resistance. v. 5, p. 135?139, 1999. KURODA, M.; OHTA, T.; UCHIYAMA, I.; BABA, T.; YUZAWA, H.; KOBAYASHI, I. Whole genome sequencing of methicillin-resistant Staphylococcus aureus. Lancet. v.357, n.9264, p.1225-1240, 2001. LANGENEGGER, J.; VIANI, M.C.E.; BAHIA, M.G. Efeito do agente etiol?gico da mastite subcl?nica sobre a produ??o de leite. Pesquisa Veterin?ria Brasileira. v.1, p. 47-52, 1981. 55 LANGONI, H. Complexidade etiol?gica na mastite bovina. Anais do III Encontro de Pesquisadores em Mastites.v.3, p 13-16, 1999. LANGONI, H.; MENDON?A, A.O.; DEVELLEY, A. Avalia??o do uso da associa??o da bromexina com gentamicina no tratamento da mastite subcl?nica bovina. Revista Napgama. n.1, p. 4-7, 2000. LAVERMICOCCA, P.; VALERIO, F.; EVIDENTE, A.; LAZZARONI, S.; CORSETTI, A.; GOBBETTI, M. Purification and characterization of novel antifungal compounds from the sourdough Lactobacillus plantarum strain 21B. Applied and Environmental Microbiology. v.66, p.4084-4090, 2000. LECLERQ, R.; COURVALIN, P. Resistance to glycopeptide in enterococci. Clinical Infectious Diseases. v.24, p.545-556, 1997. LEME, I.L.; PIANTINO, A.J.; PIGNATARI, A.C. Glycopeptides susceptibility among enterococci isolated from a poultry farm in S?o Paulo, Brazil (1996/1997). Brazilian Journal of Microbiology. v.31, p.53-57, 2000. LIVERMORE, D.M. Antibiotic resistance in staphylococci. International Journal of Antimicrobial Agents. v.16, n.1, p.3-10, 2000. LOWY, F.D. Staphylococcus aureus infections. New England Journal of Medicine. v.339, p.520-32, 1998. LOWY, F.D. Antimicrobial resistance: the example of Staphylococcus aureus. The Journal of Clinical Investigation. v.111, p.1265-1273, 2003. LU, P.L; CHING, L.C.; PENG, C.F.; CHIANG, Y.H.; CHEN, T.P.; MA, L.; SIU, L.K. Risks factors and molecular analysis of community methicillin- resistant Staphylococcus aureus carriage. Journal of Clinical Microbiology. v.43, n.1, p.132-139, 2005. MACK, D.; FISCHER, W.; KROKOTSCH, A.; LEOPOLD, K.; HARTMANN, R.; EGGE, H.; LAUFS, R. The intercellular adhesin involved in biofilm accumulation of Staphylococcus epidermidis is a linear beta-1,6-linked glucosaminoglycan, purification and structural analysis. Journal of Bacteriology. v. 178, p. 175-183, 1996. MACK, D. ROHDE, H.; DOBINSKY, S.; RIEDEWALD, J.; NEDELMANN, M.; KNOBLOCH, J. K. M.; ELSNER, H. A.; FEUCHT, H. H. Identification of three essential regulatory gene loci governing expression of Staphylococcus epidermidis polysaccharide intercellular adhesin and biofilm formation. Infection and Immunity. v. 68, p. 3799-3807, 2000. MANDELL, G.L., PETRI, W.A. Antimicrobial agents: Penicilins, cefalosporins, and others ?-lactam antibiotics. In: HARDMAN, J.G., LIMBIRD, L.E. Goodman & Gliman?s The Pharmacological Basis Of Therapeutics. 9 ed. Rio de Janeiro:McGRAWHILL, 1996. MARTINDALE. The Complete Drug Reference. 32? ed. China:Pharmaceutical Press, 1999. 56 MARTINS, R. P.; SILVA, J. A. G.; NAKAZATO, L.; DUTRA, V.; FILHO, E. S. A. Preval?ncia e etiologia infecciosa da mastite bovina na microrregi?o de cuiab?, MT. Ci?ncia Animal Brasileira. v. 11, n. 1, p. 181-187, 2010. MCMULLEN, L.M.; STILES, M.E. Potencial for use of bacteriocin producing lactic acid bacteria in the preservation of meats. Journal of Food Protection. v. 73, p.64-71, 1996. MENDON?A, C.L.; FIORAVANT, M.C.S.; SILVA, J.A.B.A.; SOUSA, M.I.; EURIDES, D.; LANGONI, H. Etiologia da mastite bovina: revis?o. Veterin?ria Not?cias. v. 5, p. 107-118, 1999. MIRLEAU, P.; DELORME, S.; PHILIPPOT, L.; MEYER, J.M.; MAZURIER, S.; LEMANCEAU, P. Fitness in soil land rhizosphere of Pseudomonas fluorecens C7R12 comparated with a C7R12 mutant affected in pyoverdine sythesis and uptake. FEMS Microbiology Ecology. v.34, p.35-44, 2000. MOHR, J.; MURRAY, B.E. Vancomycin is not obsolete for the treatment of infection caused by methicillin-resistant Staphylococcus aureus. Clinical Infection Disease. v. 44, p. 1536- 1542, 2007. MOON, J.S.; LEE, A.R.; KANG,H.M.; LEE, E.S.; KIM, M.N.; PAIK, Y.H.; PARK, Y.H.; JOO, Y.S.; KOO, H.S. Phenotypic and Genetic Antibiogram of Methicillin-Resistant Staphylococci Isolated from Bovine Mastitis in Korea. Journal of Dairy Science. v.90, p.1176-1185, 2007. MOREIRA, B.; BOYLE-VARVRA, S.; DE JONGE, B. L. M.; DAUM, R. S. Increased production of penicilin-binding protein 2, increased detection of other penicillin-binding proteins, and decreased coagulase activity associated with glycopeptides resistance in Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. v. 41, p. 1788-1793, 1997. MURRAY, B.E. Vancomycin-resistant enterococcal infections. New England Journal Medicine. v. 342, p.710-721, 2000. NAGASE, N.; SASAKI, A.; YAMASHITA, K.; SHIMIZU, A.; WAKITA, Y.; KITAI, S.; KAWANO, J. Isolation and species distribution of staphylococci from animal and human skin. Journal Veterinary Medicine Science. v.64, p.245-250, 2002. National Committee for Clinical Laboratory Standards (NCCLS). Performance standards for antimicrobial disk and dilution susceptibility test for bacteria isolated from animals; approved standard, 2nd ed. National Committee for Clinical Laboratory Standards document M31- A2. NCCLS, Wayne, PA. 2002. NAVARRO, F.; COURVALIN, P. Analysis of genes encoding d-alanine-d-alanine ligaserelated enzymes in Enterococcus casseliflavus and Enterococcusflavescens. Antimicrobial Agents Chemotherapy. v.38, p.1788?1793, 1994. NICAS, T.I.; COLE, C.T.; PRESTON, D.A. Active of glycopeptides against vancomycinresistant Gram-positive bacteria. Antimicrobial Agents Chemotherapy. v.39, p.1477-1481, 1989. 57 NOBLE, W.C.; VIRANI, Z.; CREE, R.G. Co-transfer of vancomycin and other resistance genes from Enterococcus faecalis NCTC 12201 to Staphylococcus aureus. FEMS Microbiology Letters. v.72, p.195?198, 1992. NOSKIN, G.A.; RUBIN, R.J.; SCHENTAG, J.J; KLUYTMANS, J.; HEDBLOM, E.C.; SMULDERS, M.; LAPETINA, E.; GEMMEN, E. The burden of Staphylococcus aureus infections on hospitals in the United States. Archives of Internal Medicine. v. 165, pp. 1756?1761, 2005. O'GARA, J.P. ica and beyond, biofilm mechanisms and regulation in Staphylococcus epidermidis and Staphylococcus aureus. FEMS. Microbiology Letters. v. 270, p. 179-188, 2007. OLIVEIRA, A.P.; WATTS, J. |
Page generated in 0.004 seconds