Return to search

Surtos de Enteropatia Proliferativa determinados por Lawsonia intracellularis em su?nos e coelhos no Estado do Rio de Janeiro. / Outbreaks of Proliferative Enteropathy due to Lawsonia intracellularis infection in pigs and rabbits in Rio de Janeiro State.

Submitted by Sandra Pereira (srpereira@ufrrj.br) on 2018-02-07T14:43:58Z
No. of bitstreams: 1
2007 - Carlos Torres Ribeiro.pdf: 5710755 bytes, checksum: 9715a44d07b4fa0d4b48d83f3dac6d34 (MD5) / Made available in DSpace on 2018-02-07T14:43:58Z (GMT). No. of bitstreams: 1
2007 - Carlos Torres Ribeiro.pdf: 5710755 bytes, checksum: 9715a44d07b4fa0d4b48d83f3dac6d34 (MD5)
Previous issue date: 2007-08-31 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior, CAPES, Brasil. / Outbreaks of infection by Lawsonia intracelullaris in swine and rabbits in the State of Rio de
Janeiro are described. The symptomathology was characterized by bloody and aquous
diarrhea, with respectively superacute and acute course. Post-mortem findings were a
reticulate aspect of the ileum. In swine its mucosa was moderately thickened and it contained
large amounts of partially coagulated blood; in rabbits the wall of the ileum was much
thickened and the contents were aquous. Histopathological examination revealed severe
hyperplastic proliferation of the epithelial cells of the Lieberk?hn crypts, sometimes
associated with inflammatory and necrotic alterations. Silver impregnation and
imunohistochemistry demonstrated the presence of large amounts of bacteria in the cytoplasm
of the cryptal epithelial cells. In swine L. intracellularis was seen also by ultramicroscopic
examination. This is the first report of the disease in the State of Rio de Janeiro. / Descrevem-se surtos de infec??o por Lawsonia intracellularis em su?nos e coelhos, ocorridos
no Estado do Rio de Janeiro. A sintomatologia caracterizou-se por diarr?ia sanguinolenta e
aquosa, com evolu??o superaguda e aguda, respectivamente. ? necropsia verificaram-se ?leo
de aspecto reticulado, com mucosa moderadamente espessada, contendo grande quantidade de
sangue parcialmente coagulado, no caso dos su?nos, e ?leo com parede muito espessada e
conte?do aquoso nos coelhos. O exame histol?gico revelou marcada prolifera??o hiperpl?sica
das c?lulas epiteliais das criptas de Lieberk?hn, por vezes, associada a altera??es
inflamat?rias e necr?ticas. Impregna??o pela prata e t?cnica imunoistoqu?mica demonstraram
presen?a da bact?ria, em grande quantidade, dentro do citoplasma das c?lulas epiteliais das
criptas de su?nos e coelhos. Em su?nos, L. intracellularis tamb?m foi visualizada pela
ultramicroscopia. Essa ? a primeira descri??o da enfermidade no Estado do Rio de Janeiro.

Identiferoai:union.ndltd.org:IBICT/oai:localhost:jspui/2192
Date31 August 2007
CreatorsRibeiro, Carlos Torres
ContributorsPeixoto, Paulo Fernando Vargas, Fran?a, Ticiana do Nascimento, Brito, Marilene Farias, Dobereiner, Jurgen, Torkania, Carlos Hubinger, Pitombo, C?cero Ara?jo
PublisherUniversidade Federal Rural do Rio de Janeiro, Programa de P?s-Gradua??o em Ci?ncias Veterin?rias, UFRRJ, Brasil, Instituto de Veterin?ria
Source SetsIBICT Brazilian ETDs
LanguagePortuguese
Detected LanguageEnglish
Typeinfo:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/masterThesis
Formatapplication/pdf
Sourcereponame:Biblioteca Digital de Teses e Dissertações da UFRRJ, instname:Universidade Federal Rural do Rio de Janeiro, instacron:UFRRJ
Rightsinfo:eu-repo/semantics/openAccess
RelationALEXOPOULOS, C.; TASSIS, P.D.; KYRIAKIS, C.S.; TZIKA, E.D.; PAPATSIROS, V.; KYRIAKIS, S.C. First experience on the effect of in-feed lincomycin for the control of proliferative enteropathy in growing pigs, Journal of Veterinary Medicine, v.53, p.157-162, 2006 BACCARO, M.R.; MORENO, A.M.; SHINYA, L.T.; DOTTO, D.S. Identification of bacterial agents of enteric diseases by multiplex PCR in growing-finishing pigs, Brazilian Journal of Microbiology, v. 34, p. 225-229, 2003 BARNA, P.; BILKEI, G. Effects of gilt seropositivity to Lawsonia intracellularis (LI) on their offpring?s seropositivity to LI and on diarrhoea after a pure -culture challenge, Preventive Veterinary Medicine, v. 61, p. 71-78, 2003 BIESTER, H.E.; SCHWARTE, L.E. Intestinal adenoma in swine, American Journal of Pathology, v. 7, p. 175-185, 1931. BIESTER, H.E.; SCHWARTE, L.E.; EVELETH, D.F. Studies on a rapidly developing intestinal adenoma in a pig, American Journal of Pathology, v. 15, p. 385-389, 1939 BOESEN, H.T.; JENSEN, T.K.; JUNGERSEN, G.; RIBER, U.; BOYE.; M.; MOLLER, K., Development, characterization and diagnostic application of a monoclonal antibody specific for a proteinase K resistant Lawsonia intracellularis antigen, Veterinary Microbiology, v. 10, p. 196-206, 2005 BOESEN, H.T.; JENSEN, T.K.; SCHMIDT, A.S.; JENSEN, B.B.; JENSEN, S.M.; MOLLER, K. The Influence of diet on Lawsonia intracellularis colonization in pigs upon experimental challenge, Veterinary Microbiology, v. 103, p. 35-45, 2004 BOYE, M.; JENSEN, T.K.; MOLLER, K.; LESER, T.D.; JORSAL, S.E. Specific Detection of Lawsonia intracellularis in Porcine Proliferative Enteropathy Inferred from Fluorescent rRNA In Situ Hybridization, Veterinary Pathology, v.35, n.2, p.153-156, 1998 CHIRIBOGA, A.E.C.N.; GUIMAR?ES, W.V.; VANETTI, M.C.D.; ARA?JO, E.F. Detection of Lawsonia intracellularis in faeces of swine from the main producing regions in Brazil, Canadian Journal of Microbiology, v.45, n.3, p.230-234, 1999 COOPER D.M.; SWANSON, D.L.; GEBHART, C.J. Diagnosis of proliferative enteritis in frozen and formalin-fixed, paraffin-embedded tissues from a hamster, horse, deer and 80 ostrich using a Lawsonia intracellularis-specific multiplex PCR. Veterinary Microbiology, v.54, p. 47-62, 1997 CORZO, C.A.; FRIENDSHIP, R., DEWEY, C., BLACKWELL, T. Comparition of 2 serologic tests for the diagnosis of porcine proliferative enteropathy. Canadian Veterinary Journal, v. 46, p. 433-435, 2005 DEZORZOVA-TOMANOVA, K.; SMOLA, J.; TRCKA, I.; LAMKA, J.; PAVLIK, I. Detection of Lawsonia intracellularis in wild boar and fallow deer bred in one game enclosure in the Czech republic, Journal of Veterinary Medicine, B, v.53, p.42-44, 2006 DITTMAR, M., HOELKLE, K., HOELKLE, K., SYDLER, T., CORBOZ, L., MISEREZ, R., WITTENBRINK, M. Diagnosis of Porcine Proliferative Enteropathy: Detection of Lawsonia intracellularis by Pathological Examinations, Polymerase Chain Reaction and Cell Culture Inoculation, Journal of Veterinary Medicine, 50: 332-338, 2003 DRIEMEIER, D.; FACCINI,G.S.; OLIVEIRA, R.T.; COLODEL, E.M.; TRAVERSO, S.D.; CATTANI, C. Silver staining combined with alcian blue and hematoxylin-eosin for the detection of Lawsonia intracellularis in swine proliferative enteropathy, Acta Histochemica, v.104, n.3, p. 285-287, 2002 DUHAMEL, G.E.; KLEIN, E.C.; ELDER, R.O.; GEBHART, C.J., Subclinical proliferative enteropathy in sentinel rabbits associated with Lawsonia intracellularis, Journal of Comparative Pathology, v. 35, p. 300-303, 1998 FINN, J.P.; SCHWARTZ L.W. A neoplasm of globule leukocytes in the intestine of a cat, Journal of Comparative Pathology, v.82, p. 323-328, 1972 FOX, J.G.; DEWHIRST, F.E.; FRASER, G.J.; PASTER, B.J.; SHAMES, B.; MURPHY, J.C. Intracellular Campylobacter-like organism from ferrets and hamsters with proliferative bowel disease is a Desulfovibrio sp., Journal of Clinical Microbiology, v. 32, n.5, p. 1229- 1237, 1994 FRISK, C.S.; WAGNER, J.E. Experimental hamster enteritis: an electron microscopic study, American Journal of Veterinary Research, v.38, n.11, p. 1861-1868, 1977 GAVA, D.; MORES, N.; OLIVEIRA, S.R. Avalia??o de diferentes m?todos de detec??o de Lawsonia intracellularis em tecidos parafinados. XII Congresso Brasileiro de Veterin?rios Especialistas em Su?nos ? 04 a 07 de outubro de 2005 GEBHART, C.J.; WARD, G.E.; CHANG. K.; KURT, Z.H. Campylobacter hyointestinalis (new species) isolated from swine lesion of proliferative ileitis, American Journal of Veterinary Research, Schaumburg, v.44, n.3, p. 361-367, 1983 81 GO, Y.Y.; LEE, J.K.; YE, J.Y.; LEE, J.B.; PARK, S.Y.; SONG, C.S.; KIM, S.K.; CHOI, I.S. Experimental reproduction of proliferative enteropathy and the role of IFN? in protective immunity against Lawsonia intracellularis in mice, Journal of Veterinary Science, v.6, n.4, p. 357-359, 2005 GUEDES, R.M., GEBHART, C.J. Onset and duration of fecal shedding, cell-mediated and humoral immune responses on pigs after challenge with a pathogenic isolate or attenuated vaccine strain of Lawsonia intracellularis, Veterinary Microbiology, v. 91, p. 135-145, 2001 GUEDES, R.M., GEBHART, C.J., ARMBRUSTER, G.A.; ROGGOW, B.D. Serological follow-up of a Repopulated swine herd after an outbreak of proliferative hemorrhagic enteropathy, Canadian Journal of Veterinary Research, v.66, p. 258-263, 2002a GUEDES, R.M., GEBHART, C.J., DEEN, J., WILKELMAN, N. Validation of an immunoperoxidase monolayer assay as a serologic test for porcine proliferative enteropathy, Journal of Veterinary Diagnostic and Investigation, v. 14, p. 528-530, 2002b GUEDES, R.M., GEBHART, C.J., WILKELMAN, N., MACKIE-NUSS, R.A., MARSTELLER, T.A., DEEN, J. Comparison of different methods for diagnosis of porcine proliferative enteropathy, Canadian Journal of Veterinary Research, v.66, p. 99 ? 107, 2002c HAGEN, B., BILKEI, G. Seroprevalence of Lawsonia intracellularis in large pig production units, Acta Veterinaria Hungara, v. 51, p. 165-170, 2003 HUERTA, B., ARENAS, A., CARRASCO, L. Comparison of Diagnostic techniques for porcine proliferative enteropathy (Lawsonia intracellularis infection), Journal of Comparative Patholology, v. 129, p. 179-185, 2003 HUTCHKISS, C.E.; SHAMES, B.; PERKINS, S.E.; FOX, J.G. Proliferative enteropathy of rabbits: the intracellular Campylobacter-like organism is closely related to Lawsonia intracellularis, Laboratory Animal Science, v. 46, p. 623-627, 1996 JACOBSON, M.; SEGERSTAD, C.H.; GUNNARSSON, A. et al. Diarrhoea in the growing pig ? a comparison of clinical, morphological and microbial findings between animals from good and poor performance herds, Research in Veterinary Science, v. 74, p. 163-169, 2003 82 JACOBSON, M.; LOFSTEDT, M.D.; HOMGREN, N. et al. The prevalences of Brachyspira spp. and Lawsonia intracellularis in Swedish piglet producing herds and wild boar population, Journal of Veterinary Medicine, v. 52, p. 386-39, 2005 JENSEN, T.K.; CHRISTENSEN, B.B.; BOYE, M. Lawsonia intracellularis in the large intestine of pigs, APMIS, v. 114, p. 255-264, 2006 JENSEN, T.K.; MOLLER, K.; LINDECRONA, B.; JORSAL, S.E. Detection of Lawsonia intracellularis in the tonsils of pigs with proliferative enteropathy, Research in Veterinary Science,v. 68, p. 23-25, 2000 JENSEN, T.K.; VIGRE, H.; SORENSEN,V.; MOLLER, K. Naturally acquired Lawsonia intracellularis in pigs studied from weaning to slaughter by indirect immunofluorescence antiboby test and polymerase chain reaction on feaces, Research in Veterinary Science, v. 79, p. 93 ? 98, 2005 JONES, G.F.; WARD, G.E.; MURTAUGH, M.P.; LIN, G.; GEBHART, C.J. Enhanced detection of intracellular organism of swine proliferative enteritis, ileal symbiont intracellularis, in feces by polymerase chain reaction, Journal of Clinical Microbiology, v. 31, n.10, p. 2611-2615, 1993 JUBB, K.V.F.; KENNEDY, P.C.; PALMER, N. Pathology of Domestic Animals, Academic Press, 4a edi??o, 1993 JUST, S.D., THOEN, C.O., THAKER, B.J., THOMPSON, J.U., Monitoring of Lawsonia intracellularis by indirect serum immunofluorescence assay in a commercial swine production system, Swine Health and Production, v. 9, p. 57-61, 2000 KIM, J., CHOI, C., CHO, W.S., CHAE, C. Immunohistochemistry and Polymerase Chain Reaction for detection of Lawsonia intracellularis in porcine intestinal tissues with Proliferative Enteropathy, Journal of Veterinary Medical Science, v. 62, n. 2, p. 771-73, 2000 KOYAMA,T.; HIRAI, T.; NAGAI, S. In vitro cultivation and Partial Characterization of Lawsonia intracellularis from a Japanese Field Case of Porcine Proliferative Enteropathy, Journal of Veterinary Medical Science, v. 68, n. 8, p. 609-611, 2006 KROLL, J.J.; EICHMEYER, M.A.; SCHAEFFER, M.L.; McORIST, S.; HARRIS, D.L.; ROOF, M.B. Lipopolysaccharide -based enzyme-linked immunosorbent assay for experimental use in detection of antibodies to Lawsonia intracelullaris in pigs, Clinical and Diagnostic Laboratory Immunology, v. 12, n. 6, p. 693-699, 2005 83 KYRIAKIS, S.C.; ALEXOPOULOS, C.; SAOULIDIS, K.; LEKKAS, S.; MILLIOTIS, C.C.; SAUVEROCHE, B. The effect of josamycine on the control of ileitis in weaned piglets under field conditions, Journal of Veterinary Pharmacology and Therapeutics, v. 25, p. 279- 284, 2002a KYRYAKIS, S.C.; HATZOPOULOU, E.B.; ALEXOPOULOS, C.; KRITAS, S.K.; POLYZOPOULOU, Z.; LEKKAS, S.; GARDEY, L. Field evaluation of the effect of in feed doxycyclin for the control of ileitis in weaned piglets, Journal of Veterinary Medicine, v. 49, p. 317-321, 2002b LAWSON, G.H.; McORIST, S.; ROWLAND, A.C.; McCARTNEY, E.; ROBERTS, L. Serological diagnosis of the porcine proliferative enteropatihes: implicationsfor aetiology and epidemiology, Veterinary Record, v. 122, n. 23, p. 554-557, 1988 LAWSON, G.H.; ROWLAND, A.C.; MaCINTYRE, N. Demonstration of a new intracellular antigen in porcine intestinal adenomatosis and hamster proliferative ileitis, Veterinary Microbiology, v. 10, n. 4, p. 303-313, 1985 LAWSON, G.H.K., ROWLAND, A.C., ROBERTS, L., FRASER, G., MCCARTNEY, E Proliferative haemorrhagic enteropathy, Research Veterinary Science, v. 27, p. 46-51, 1974 LAX, A.J.; THOMAS, W, How bacteria could cause cancer: one step at a time, Trends in Microbiology, v. 10, n. 6, p.293-299, 2002 LEMARCHAND, T.X.; TULLY, T.N.; SHANE, S.M.; DUNCAN, D.E. Intracellular Campylobacter-like organism associated with rectal prolapse and proliferative enteroproctitis in emus (Dromaius novaehollandiae), Veterinary Pathology, v. 34, p. 152- 156, 1997 LOVE, R.N.; LOVE, D.N.; EDWARDS, M.J. Proliferative Haemorrhagica enteropathy in pigs, Veterinary Record, London, v. 100, n. 4, p. 65-8, 1977 MacINTYRE, N.; SMITH, D.G.E.; SHAW, D.J.; THOMSON, J.R.; RHIND, S.M. Immunopathogenesis of experimentally induced Proliferative Enteropathy in pigs Veterinary Pathology, v. 40, p. 421-432, 2003 MAPOTHER, M.E.; JOENS, L.A.; GLOCK, R.D. Experimental reproduction of porcine proliferative enteritis, Veterinary Record, v. 121, p. 533-536, 1987 84 MAUCH, C.P.; BILKEI, G., Reproductive performance of gilts following na outbreak of acute proliferative enteropathy due to Lawsonia intracellularis, Veterinary Journal, v. 170, p. 128-31, 2005 McCLUSKEY; J.; HANNIGAN; J.; HARRIS, J.D.; WREN, B.; SMITH, D.G.E. LsaA, an antigen involved in cell attachment and invasion, is expressed by Lawsonia intracellularis during infection in vitro and in vivo, Infection and Immunity, v. 70, n. 6, p. 2899-2907, 2002 McORIST, S. Defining the full costs of endemic porcine proliferative enteropathy, The Veterinary Journal, v. 170, p. 8-9, 2005 McORIST, S.; BOID, R.; LAWSON, G.H.K. Antigenic analysis of Campylobacter species and an intracellular Campylobacter-like organism associated with Porcine Proliferative Enteropathies, Infection and Immunity, v.57, n. 3, p. 957-962, 1989 McORIST, S.; MacINTYRE, N.; STOKES, C.R.; LAWSON, G.H.K. Immunocytological responses in porcine proliferative enteropathies, Infection and Immunity, v. 60, p. 4184- 4191, 1992 McORIST, S.; GEBHART; C.J.; BOID, R.; BARNS, S.M. Characterization of lawsoniaintracellularis gen-nov, sp-nov, the obligately intracellular bacterium of porcine proliferative enteropathy, International Journal of Systematic Bacteriology, v. 45, n.4, p. 820-825, 1995 McORIST, S.; JASNI, S.; MACKIE, R.; MacINTYRE, N.; NEEF, N.; LAWSON, G. Reproduction of porcine proliferative enteropathy with pure cultures of ileal symbiont intracellularis, Infection and Immunology, v. 61, n. 10, p. 4286-4292, 1993 McORIST, S., SMITH, S.H., GREEN, L.E. Estimate of Direct financial losses due to porcine proliferative enteropathy, Veterinary Record, v. 140, p. 579-581, 1997 MOON, H.W.; CUTLIP, R.C.; AMTOWER, W.C.; MATTHEWS, P.J. Intraepitelial Vibrio associated with acute typhlitis of young rabbits, Veterinary Pathology, v. 11, p. 313-326, 1974 MORENO, A.M. Enterite Proliferativa Su?na: Aspectos cl?nico-patol?gicos e epidemiol?gicos, 1v., 55p., Universidade de S?o Paulo, Patologia Experimental e Comparada, Tese defendida em 01/11/1999 85 MOR?S, N.; NEVES, D.S.; NOGUEIRA, R.H.G.; GUIMAR?ES, E.B. Diagn?sticos cl?nico e An?tomo-Histol?gicos de Casos espont?neos de Enteropatia Proliferante e Hemorr?gica (EPH) em su?nos, Arquivo Brasileiro de Medicina Veterin?ria e Zootecnia, v. 37, n.1, p. 29-37, 1985 PEARCE, G.P. Interactions between dietary fibre, endo -parasites and Lawsonia intracellularis bacteria in grower-finisher pigs, Veterinary Parasitology, v. 87, p. 51-61, 1997 PLAWINSKA, J.; BINEK, M. Lawsonia intracellularis ? The causative agent of Porcine Proliferative Enteritis, Medycyna Weterynaryjna, v. 62, n. 8, p. 860-864, 2006 ROBERTS, L.; ROWLAND, A.C.; LAWSON, G.H.K. Experimental reproduction of porcine intestinal adenomatosis and necrotic enteritis, Veterinary Record, v. 100, p. 12-13, 1977 RODR?GUEZ, J.C.; ALVAREZ, M.; RODR?GUEZ, L.; SEGURA, J.C. A longitudinal study of porcine proliferative enteropathy in a commercial pig farm in Yucatan Mexico, Arquivo Brasileiro de Medicina Veterin?ria e Zootecnia, v. 57, n. 3, p. 401-404, 2005 ROWLAND, A.C.; HUTCHINGS, D.A. Necrotic enteritis and regional ileitis in pigs at slaughter, Veterinary Record, London, v. 103, n. 15, p. 338-339, 1978 ROWLAND, A.C.; LAWSON, G.H.K. Porcine intestinal adenomatosis: a possible relationship with necrotic enteritis, regional ileitis and proliferative haemorrhagic enteropathy, Veterinary Record, London, v. 97, n. 10, p. 178-180, 1975 ROWLAND, A.C.; LAWSON, G.H.K. Porcine proliferative enterophaties, In: LEMAN, A.D.; STRAW, B.E.; MENGELING, W.L.; D?ALLAIRE, S.; TAYLOR, D.J. (Eds.), Diseases of Swine , 7a Edi??o, Iowa State University Press, Iwoa, pp. 560-569, 1992 ROWLAND, A.C.; ROWNTREE, P.G.M. Haemorrhagic Bowel Syndrome associated with intestinal adenomatosis in the pig, Veterinary Record, v. 91, p. 235-241, 1972 RUEMMELE, F.C.; GURBINDO, C.; MANSOUR, A.M.; MARCHAND. R.; LEVY, E.; SEIDMAN, E.G. Effects of interferon gamma on growth, apoptosis, and MHC class II expression of immature rat intestinal crypt (IEC-6) cells, Journal Cell Physiology, v.176, n. 1, p. 120-126, 1998 apud SMITH, D.G.E.; MITCHELL, S.C.; NASH, T.; RHIND, S. Gamma interferon influences intestinal epithelial hype rplasma caused by Lawsonia intracellularis infection in mice, Infection and Immunology, v. 68, p. 6737-6743, 2000 86 SCHAUER, D.B., MCCATHEY, S.N., DAFT, B.M. et al. Proliferative Enterocolitis associated with dual infection with Enteropathogenic Escherichia coli and Lawsonia intracellularis in rabbits, Journal of Clinical Microbiology, v. 36, n. 6, p. 1700-1703, 1998 SEGAL?S, J; FERN?NDEZ-SALGUERO, J.M.; FRUCTUOSO, G.; QUINTANA, J.;. ROSELL, J. POZO, J.; ARRIBA, M.L; RUBIO, M.; DOMINGO, J. Granulomatous Enteritis and Lymphadenitis in Iberian Pigs Naturally Infected with Lawsonia intracellularis Veterinary Pathology, v. 38, n. 3, p. 343?346, 2001 SMITH, D.G.E.; MITCHELL, S.C.; NASH, T.; RHIND, S. Gamma interferon influences intestinal epithelial hyperplasma caused by Lawsonia intracellularis infection in mice, Infection and Immunology, v. 68, p. 6737-6743, 2000 SMITH D.G.E, LAWSON GH. Lawsonia intracellularis: getting inside the pathogenesis of proliferative enteropathy. Veterinary Microbiology, v. 82, n.4, p. 331-334, 2001 SONNE, L.; PESCADOR, C.A.; ZLOTOWSKI, P.; BOHRER, P.V.; MOLETA, E.C.; CASTAGNA, S.M.F.; BESSA, M.C.; DRIEMEIER, D. , Mortalidade de coelhos associada a Enteropatia Proliferativa causada por Lawsonia intracellularis no Rio Grande do Sul. Anais do XI Encontro Nacional de Patologia Veterin?ria, 21 a 25 de julho de 2003, Botucatu STEGE, H.; JENSEN, T.K.; MOLLER, K.; VESTERGAARD, K.; BAEKBO, P.; JORSAL, S.E. Infection dynamics of Lawsonia intracellularis in pig herds, Veterinary Microbiology, v. 9, n. 3-4, p. 197-206, 2004c STEGE, H., JENSEN, T.K., M?LLER, K., BAEKBO, P., JORSAL, S.E. Prevalence of intestinal pathogens in Danish finishing pig herds. Veterinary Records, v. 46, p. 279-292, 2000 SUH, D.K.; LYM, S.K.; BAE, Y.C.; LEE, K.W.; CHOI, W.P.; SONG, J.C. Detection of lawsonia intracelularis in diagnostic specimens by one -step PCR, Journal of Veterinary Science, v. 1, n. 1, p. 33-37, 2000 SUH, D.K.; SONG, J.C. Prevalence of Lawsonia intracellularis, Brachyspira hyodysenteriae and Salmonella in swine herds, Journal of Veterinary Science, v. 6, n. 4, p. 289-293, 2005 TOMATOV?, K., LITER?K, I., KLIMES, J. Lawsonia intracellularis in wild mammals in the Slovak Carpathians , Journal of Wildlife Disease, v.39, n.2, p. 407-411, 2003 87 UMEMURA, T.; TSUCHITANI, M.; TOTSUKA, M.; NARAME, I.; YAMACHIRO, S. Histiocytic Enteritis of Rabbits, Veterinary Pathology, v. 19, p. 326-28, 1982 WATARAI, M., YAMATO, Y., HORIUCHI, N.; KIM, S.; OMATA, Y.; SHIRAHATA, T.; FURUOKA, H. Enzyme-Linked Immunosorbent Assay to Detect Lawsonia intracellularis in rabbits with Proliferative Enteropathy, Journal of Veterinary Medical Science, v. 66, n. 6, p. 735-737, 2004 WATARAI, M., YAMATO, Y., MURAKATA, K.; KIM, S.; OMATA, Y.; FURUOKA, H. Detection of Lawsonia intracellularis Using Immunomagnetic Beads and ATP Bioluminescence, Journal of Veterinary Science, v. 67, n. 4, p. 449-451, 2005 WUERSCH, K.; HUESSY, D.; KOCH, K., Lawsonia intracellularis Proliferative Enteropathy in a Filly, Journal of Veterinary Medicine, v. 53, p. 17?21, 2006 YATES, W.D.G.; CLARK, E.G.; OSBORNE, A.D.; ENWEANI, C.C.; RADOSTITS, O.M.; THEEDE, A. Proliferative Hemorrhagic Enteropathy: An Outbreak and Review of the literature, Canadian Veterinary Journal, v. 20, p. 261-268, 1979 YEH, J.Y.; KIM, T.J.; PARK, S.Y.; SONG, S.G.; YOON, Y.D.; KIM, S.K.; LEE, J.B.; CHOI, I.S. Isolation of Lawsonia intracellularis in Korea and reproduction of proliferative enteropathy in pigs and hamsters, Journal of Veterinary Medicine Science, v. 68, n.5, p. 499-501, 2006

Page generated in 0.0019 seconds