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amancio_fam_dr_botfm.pdf: 670317 bytes, checksum: 8b76b4aa24f2fa74d9a2b243107566d5 (MD5) / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / Universidade Estadual Paulista (UNESP) / O trato gastrointestinal desempenha papel critico na patogenia da aids sendo as alterações clinicas principalmente associados a parasitoses. O presente estudo avaliou as variáveis epidemiológicas, nutricionais e imunológicas nos indivíduos HIV positivos com e sem enteroparasitoses. Foram avaliados 105 indivíduos, 54 (51,43%) do sexo masculino . A média de idade dos não parasitados foi de 40,19 ± 10,39 anos e dos parasitados 44,15 ± 10,86. Todos foram atendidos no Serviço de Ambulatórios Especializados e Hospital Dia Professor Emérito Domingos Alves Meira em Botucatu/UNESP. Foi aplicado questionário socioeconômico, aferido peso e altura para cálculo de IMC e coletadas 3 amostras de fezes para exame parasitológico (método TFtest ® ) e 5ml de sangue para avaliação de eosinófilos , albumina IgE , contagem de linfócitos TCD4+ e TCD8+ , carga viral e quantificação das citocinas TNF-N, INF-d, IL-2, IL-5 e IL-10 em ambos os grupos. Dentre os 105 indivíduos analisados, 92 (87,6%) apresentaram resultados negativos para enteroparasitoses e 13 (12,38%) resultados positivos. Entamoeba coli foi encontrada em 5 (38,5%) das amostras, Giardia lamblia 4 (30,7%), Blastocystis hominis 3 (23.0%), Endolimax nana 2 (15.4%) e Ascaris lumbricoides 1 (7.7%). A maioria dos indivíduos (97,15 %) apresentava bom nível de escolaridade, todos com saneamento básico, moradia em área urbana (95,23%), com água e esgoto tratados, a minoria (26,66%) fazendo uso de horta. Eutrofia e sobrepeso esteve presente em 50% e 31,39 % respectivamente e a maioria ( 88,57%) em uso de TARV. Os níveis séricos de eosinófilos dos indivíduos variaram de 0 a 1948 células/mm3 e não houve diferença significativa entre os 2 grupos analisados (p = 0.3198). Os níveis séricos de albumina variaram de 2.6 a 6.8 g/dl e não... / The gastrointestinal tract plays a critical role in AIDS pathogeny, and clinical alterations are mainly associated with parasitic diseases. The present study evaluated the epidemiological, nutritional and immunological variables in HIV positive individuals with and without enteroparasites. One hundred and five individuals were evaluated, of whom 54 (51.43%) were males. The mean age of non-parasitized individuals was 40.19 ± 10.39 years, and that of parasitized persons was 44.15 ± 10.86. All of them were given care at the Specialized Outpatient Service Units of Day Hospital Emeritus Professor Domingos Alves Meira in Botucatu/UNESP. A socioeconomic questionnaire was applied; weight and height were measured for BMI estimation; 3 stool samples were collected for parasitological testing (TF-test® method), and 5ml of blood were used for assessment of eosinophils, albumin IgE, TCD4+ and TCD8+ lymphocyte count, viral load and quantification of cytokines TNF-N, INF-X, IL-2, IL-5 and IL-10 in both groups. Among the 105 individuals analyzed, 92 (87.6%) showed negative results for enteroparasites, and 13 (12.38%) showed positive results. Entamoeba coli was found in 5 (38.5%) samples, Giardia lamblia in 4 (30.7%), Blastocystis hominis in 3 (23.0%), Endolimax nana in 2 (15.4%) and Ascaris lumbricoides in 1 (7.7%). Most of the individuals (97.15 %) had a good education level, access to basic sanitation and lived in urban areas (95.23%) with treated water and sewage, and the minority (26.66%) grew a vegetable garden. Eutrophy and overweight were present in 50% and 31.39 %, respectively, and most individuals (88.57%) used ARVT. The individuals' eosinophil serum levels ranged from 0 to 1,948 cells/mm3, and no significant difference was found between the 2 studied groups (p = 0.3198). Their serum levels of albumin... (Complete abstract click electronic access below)
| Identifer | oai:union.ndltd.org:IBICT/oai:repositorio.unesp.br:11449/101480 |
| Date | 07 February 2010 |
| Creators | Amâncio, Fátima Aparecida Mazzini [UNESP] |
| Contributors | Universidade Estadual Paulista (UNESP), Pereira, Paulo Câmara Marques [UNESP] |
| Publisher | Universidade Estadual Paulista (UNESP) |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/doctoralThesis |
| Format | 75 f. |
| Source | Aleph, reponame:Repositório Institucional da UNESP, instname:Universidade Estadual Paulista, instacron:UNESP |
| Rights | info:eu-repo/semantics/openAccess |
| Relation | -1, -1 |
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