Orientador : Maria Beatriz Puzzi / Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas / Made available in DSpace on 2018-08-03T15:10:26Z (GMT). No. of bitstreams: 1
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Previous issue date: 2003 / Resumo: Foram apresentados os resultados de um estudo com 12 pacientes portadores de vitiligo estável, tratados com quatro diferentes técnicas cirúrgicas, aplicadas em cada paciente de forma concomitante; num total de 48 áreas tratadas e seguidas ao longo de 90 dias. Efetuaram-se os seguintes tratamentos: tratamento apenas com crioterapia (AC); crioterapia mais meio de cultura para melanócitos (CM); crioterapia mais transplante de melanócitos e queratinócitos não em cultura (QM); crioterapia mais transplante de melanócitos em cultura (CC). Acompanhou-se o aparecimento e evolução da repigmentação ao longo do tempo.
Não houve repigmentação em AC e CM. Houve repigmentação progressiva em QM e CC, ao longo dos 90 dias. O nível de redução da área acrômica em ambos foi significativa ao longo dos 90 dias. Não houve, porém, diferença significativa entre ambos / Abstract: This study presents the results of a clinical trial study, conducted on 12 patients with stable vitiligo at the vitiligo outpatient clinic of The Clinical Hospital of the University of Campinas, between March 2000 and December 2001. This study was in accordance with the ethical standards of the Institutional Review Board. The patients were concomitantly treated with four different types of surgical techniques in 48 areas randomly chosen. There was a 90-day follow-up period. The following treatments were carried out: only cryotherapeutic treatment (OC); cryotherapy plus melanocyte culture medium (CM); cryotherapy plus transplantation of non-cultured melanocytes and keratinocytes (KM); and cryotherapy plus transplantation of cultured melanocytes (CC). The appearance of repigmentation and its evolution were followed all along the treatments. In the case of OC and CM no repigmentation occurred. Progressive repigmentation was observed over a period of 90 days in the case of KM and CC. In these two groups there was a significant reduction in the achromic areas during this time but no significant difference was found between the two treatments / Doutorado / Clinica Medica / Doutor em Clínica Médica
| Identifer | oai:union.ndltd.org:IBICT/oai:repositorio.unicamp.br:REPOSIP/313298 |
| Date | 03 August 2018 |
| Creators | Issa, Claudia Maria Bernardino Magro |
| Contributors | UNIVERSIDADE ESTADUAL DE CAMPINAS, Puzzi, Maria Beatriz, 1950- |
| Publisher | [s.n.], Universidade Estadual de Campinas. Faculdade de Ciências Médicas |
| Source Sets | IBICT Brazilian ETDs |
| Language | Portuguese |
| Detected Language | English |
| Type | info:eu-repo/semantics/publishedVersion, info:eu-repo/semantics/doctoralThesis |
| Format | 150p. : il., application/pdf |
| Source | reponame:Repositório Institucional da Unicamp, instname:Universidade Estadual de Campinas, instacron:UNICAMP |
| Rights | info:eu-repo/semantics/openAccess |
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