Genetic variation in disease resistance was investigated in two coho salmon
(Oncorhynchus kisutch) strains, previously demonstrated to have significant differences
in survival after challenge with the marine fish pathogen Vibrio anguillarum, and their
reciprocal strain crosses. V. anguillarum and the freshwater fish pathogen Aeromonas
salmonicida were used in the disease challenges conducted by immersion, injection and
cohabitation with infected cohorts. Kidney and gill lysozyme activity, white blood cell
counts and hemoglobin concentration were determined following V. anguillarum
immersion challenge of the pure strains and the strain-crosses. Overall, disease resistance
among the strains after challenge with the two bacterial pathogens, by all methods of
disease challenge, was not significantly different. Significant differences among the
strains in non-specific immune parameters both before and after bacterial infection were
described. As well, a significant treatment effect in lysozyme activity demonstrated that
the bacterial challenges stimulated the non-specific immune system. No significant
advantage to disease resistance against either vibriosis or furunculosis is likely to be
gained by crossing the Quinsam River and Robertson Creek strains of coho salmon.
Further, the inter-strain crosses did not appear to have an increased activity of the nonspecific
immune system relative to the parent strains.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:BVAU.2429/11829 |
| Date | 11 1900 |
| Creators | Roome, Jennifer Robyn |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Relation | UBC Retrospective Theses Digitization Project [http://www.library.ubc.ca/archives/retro_theses/] |
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