Stroke is a leading cause of disability in Canada. To maximize a patient's chance of
returning to their pre-stroke state, rehabilitation programs must be tailored to their specific brain impairments. Unfortunately, assessment of post-stroke impairments is largely based on the perceptual decisions of a clinician. To ensure inter-rater
reliability, many current assessment tools use coarse, ordinal scales resulting in
floor and ceiling effects.
The purpose of this thesis was to use robotic technology coupled with a visually
guided reaching task to develop a reliable and sensitive tool for assessing upper limb
motor function after stroke. Robotic devices have contributed greatly to our under-
standing of motor function because of their ability to objectively, repeatedly, and
reliably measure behavior. Visually guided reaching is an ideal task for assessing up-
per limb motor function because it requires a broad range of sensorimotor functions
as well as healthy functioning of a diverse neural network.
Control and stroke subjects performed an unassisted visually guided reaching task
with each arm using the KINARM robot. Sensorimotor functions were assessed using
a broad range of parameters derived from the kinematics of movement.
In our first study we examined the reaching performance of subjects with subacute stroke and reliably found impairments in both their affected and unaffected arms. We also found performance asymmetries between the affected and unaffected arms that were present even when both arms demonstrated normal reaching behaviour independently.
In our second study we examined changes in reaching performance that occur over
the first six months following stroke. We found that with time reaching performance
improved with both arms, but performance asymmetries persisted throughout the first six months after stroke.
In our final study we examined reaching performance of healthy adults between
the ages of 20 and 84 years of age. We found linear declines with age across most of
our movement parameters, but interlimb asymmetries to be stable across adulthood.
To generate age-specific performance curves descriptive statistics were tabulated for
each parameter.
The results of this thesis demonstrate that a visually guided reaching task can
provide reliable and sensitive information about a subject's sensorimotor impairments
following stroke. / Thesis (Ph.D, Neuroscience Studies) -- Queen's University, 2011-04-21 15:16:11.342
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:OKQ.1974/6384 |
| Date | 21 April 2011 |
| Creators | Coderre, Angela Marie |
| Contributors | Queen's University (Kingston, Ont.). Theses (Queen's University (Kingston, Ont.)) |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English, English |
| Detected Language | English |
| Type | Thesis |
| Rights | This publication is made available by the authority of the copyright owner solely for the purpose of private study and research and may not be copied or reproduced except as permitted by the copyright laws without written authority from the copyright owner. |
| Relation | Canadian theses |
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