Histological examination of the brains of experimental animals subjected to convulsive seizures shows an evidence of tissue damage which could be the result, to some extent, of increased vascular permeability. Diapedesis of red cells, edema and nerve cell damage in acute stages, and perivascular hematogenous pigment, nerve cell deficit and gliosis around the blood vessels in chronic conditions are examples of such changes. More direct evidence was obtained in experiments in which trypan blue was used to test the permeability of the blood-brain barrier (BBB) in various pathological conditions - among others, in the electrically-induced epileptic seizures.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.110302 |
| Date | January 1956 |
| Creators | Rozdilsky, Bohdan. |
| Contributors | Olszewski, J. (Supervisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science. (Department of Neurology and Neurosurgery) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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