The work of Bourchadat and Sandras (1) was the first recorded attempt to determine the fate of ethanol in the body. They suggested that ethanol is completely burned in the organism to carbon dioxide. Although this observation was confirmed by others, the general belief persisted that ethanol was not oxidised at all, but was eliminated unchanged (2). This theory was based on the results of the animal experiments formed about 1870 which showed that ethanol appeared both in the urine and expired air. Later, Dupre, Anstie and others (3,4,5,6) found that most of the administered ethanol disappears and that the amounts recovered in the urine represent only a very small fraction of the original dose.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.112011 |
| Date | January 1959 |
| Creators | Majchrowicz, Edward. |
| Contributors | Quastel, J. (Supervisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Doctor of Philosophy. (Department of Chemistry.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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