The work to be presented in this thesis concerns the divergent pathways of tryptophan metabolism to the 5-hydroxyindoles and to kynurenine. More specifically an attempt has been made to elucidate the role of dietary tryptophan in the operation of these two pathways. Previous investigators have implied that thiamine is involved in the kynurenine-forming pathway. Both nutritional studies and experiments in vitro were carried out to determine just where thiamine (or thiamine pyrophosphate, its coenzyme form) exerts its action.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.112099 |
| Date | January 1959 |
| Creators | Townsend, Edith. E. |
| Contributors | Sourkes, T. (Supervisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Doctor of Philosophy. (Department of Chemistry.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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