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Alternate pathways of tryptophan metabolism in the rat.

The work to be presented in this thesis concerns the divergent pathways of tryptophan metabolism to the 5-hydroxyindoles and to kynurenine. More specifically an attempt has been made to elucidate the role of dietary tryptophan in the operation of these two pathways. Previous investigators have implied that thiamine is involved in the kynurenine-forming pathway. Both nutritional studies and experiments in vitro were carried out to determine just where thiamine (or thiamine pyrophosphate, its coenzyme form) exerts its action.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.112099
Date January 1959
CreatorsTownsend, Edith. E.
ContributorsSourkes, T. (Supervisor)
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageDoctor of Philosophy. (Department of Chemistry.)
RightsAll items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.
Relationalephsysno: NNNNNNNNN, Theses scanned by McGill Library.

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