The present study was carried out to evaluate the osteoconductive nature of Bio-OssRTM (natural deproteinized bone mineral) when used as an onlay bone substitute in a Guided Bone Regeneration model. The lateral surface of the mandible was exposed bilaterally, in 8 rabbits. On one side of the mandible, two titanium chambers were filled with Bio-OssRTM material and the chambers were then firmly secured to the mandible using screws. The pores in the titanium chambers were covered with a layer of Bio-GideRTM material. On the opposite side of the mandible, chambers without Bio-OssRTM were placed on the lateral side of the mandible as a control. After a healing period of 3 months, histologic sections were obtained from each chamber. It was observed that new bone was generated in both test and control chambers to various degrees. In the test group, the newly generated bone was 18.41% and in the control group it was 5.31%. This difference was statistically significant. Thus, in this experiment, Bio-OssRTM was proven to be osteoconductive.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.112372 |
| Date | January 2008 |
| Creators | Al-Harkan, Abdullah. |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science (Faculty of Dentistry.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 002699176, proquestno: AAIMR51061, Theses scanned by UMI/ProQuest. |
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