The introduction of the tissue slice technique by Warburg and his associates markedly facilitated in vitro metabolic studies. In 1924 Warburg reported that rat brain cortex slices incubated in a glucose-Ringer medium yielded an oxygen quotient (Qo2) of 10.7. Though higher rates have been recorded for the Qo2 of brain cortex slices in normal physiological media, these values have invariably been round to be lower than those calculated for the brain in vivo. Elliott estimating the respiratory rates of the whole brain invitro found that they approximate the rates observed in vivo in conditions of diminished functional activity.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.115109 |
| Date | January 1963 |
| Creators | Haber, Andrew. B. |
| Contributors | Quastel, J. (Supervisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Doctor of Philosophy. (Department of Chemistry.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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