Interest in acetylcholine (ACh) as a chemical transmitter in the central nervous system was developed many years ago when attempts were made to determine the mechanism of transmission of impulses occurring (a) across ganglionic synapses and (b) from motor nerve endings to the motor endplates of skeletal muscle. Although ACh was synthesized in 1867 (1) and Elliott in 1904 (2) firmly suggested the concept of humoral transmission when he found marked functional similarities between the effects of sympathetic nervous stimulation and that of adrenaline action, it was not until 1906, that Hunt and Taveau (3) proved ACh to be a nerve depressor.
Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.115233 |
Date | January 1963 |
Creators | Samad, Roushan. A. |
Contributors | Hosein, E. (Supervisor) |
Publisher | McGill University |
Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
Language | English |
Detected Language | English |
Type | Electronic Thesis or Dissertation |
Format | application/pdf |
Coverage | Doctor of Philosophy. (Department of Chemistry.) |
Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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