During the past three decades, following the isolation of ascorbic acid from bovine adrenal glands (1), there have been many investigations concerning the possible role of this vitamin in adrenal function. The elucidation of the mechanism and significance of ACTH (adrenocorticotrophic hormone) induced depletion of ascorbic acid is still a major problem in adrenocortical physiology. Ascorbic acid occurs in two forms, one being the oxidation product of the ether. Both forms are biologically active. They are water soluble, insoluble in organic solvents, and unstable when exposed to oxygen, light, alkalies and certain metals. The most prominent chemical property of ascorbic acid is its ready oxidation to dehydroascorbic acid, which is catalyzed by small concentrations of metal ions.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.115245 |
| Date | January 1963 |
| Creators | Sharma, Shail. K. |
| Contributors | Quastel, J. (Supervisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Doctor of Philosophy. (Department of Chemistry.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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