Almost one hundred years ago Paul Langerhans (1) described the pancreatic islet cells. Another 50 years had passed before its physiological significance had become clear, following the studies of Laguesse (2). On the basis of histological observations, particularly referring to profuse vascularization of the islets, Laguesse suggested in 1893, that islet cell have an endocrine function. The classical experiments of Banting and Best (3) in 1922 lead to the identification of the hormone insulin and consequently to the treatment of diabetes. According to present knowledge, insulin is secreted by Beta cells. It has been shown that the insulin content of the splenic portion of the dog's pancreas is much higher than the duodenal portion.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.115388 |
| Date | January 1964 |
| Creators | Chun, John. Y. |
| Contributors | Skoryna, S. (Supervisor) |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science. (Department of Health Sciences.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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