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Strain differences in the teratogenic effects of 6-aminonicotinamide in mice.

Although the fact that man might produce malformed offspring in animals by altering the maternal environment was stated in the Bible (Genesis 30), when Jacob caused Laban’s sheep and goats to have striped and speckled young by holding striped rods in front of the females at the moment of conception, experimental teratology is a relatively new field. Hale, the first scientific mammalian experimental teratologist, produced a litter of 11 eyeless pigs by feeding the mother a vitamin A deficient diet (1933). At the present time most teratologist, have progressed from merely producing malformations and enumerating them, to making use of the malformations for the study of their pathogenesis and the role played by the genetic background of the mother and embryo in the production of the malformation in question.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.115508
Date January 1964
CreatorsGoldstein, Marc. B.
ContributorsFraser, F. (Supervisor)
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageMaster of Science. (Department of Biology.)
RightsAll items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.
Relationalephsysno: NNNNNNNNN, Theses scanned by McGill Library.

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