Recent projects in this laboratory have been devoted to the study of a number of problems related to acute experimental pancreatitis. The first of a series of findings in this field of endeavour was the demonstration that a uniformly fatal form of acute haemorrhagic pancreatitis could be induced in the dog. With this tool in hand, further experiments implicated the release of bradykinin in the pathogenesis of the clinical manifestations of the glandular insult. It was simultaneously shown that the proteinase inhibitor Trasylol (FBA Pharmaceuticals) could favourably alter the mortality rate of animals inflicted with this disease and appreciably decrease the amount of active bradykinin released in the course of experiments. [...]
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.116612 |
| Date | January 1964 |
| Creators | Popieraitis, Anthony S. |
| Contributors | Thompson, A. G. (Supervisor), Gabor, Ivan., Moffat, J. G., Trank, J. W., Gurd, F. N. |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science. (Department of Experimental Surgery.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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