The complete cycle of albumin metabolism is now known in its broadest outline. The site of albumin synthesis had long been implicated to be in the liver by clinical observations and more recent studies on isolated perfused rat liver with radioactive labelled amino acid have confirmed these impressions, but the mechanism of its breakdown remained to be elucidated until 1959 Birke et al. and 1960 Wetterfors et al. demonstrated that a large percentage of breakdown occurred in the stomach and small intestine. In 1961, Katz et al. demonstrated the rate of catabolism of albumin in rats to be about 20% in the gastrointestinal tract, 25% in the liver and 50% in the muscle and skin. [...]
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.116691 |
| Date | January 1964 |
| Creators | Sum, Peter T-Y |
| Contributors | Hoffman, M. M. (Supervisor), Webster, D., Miller, W. D. |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science. (Department of Experimental Surgery.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: NNNNNNNNN, Theses scanned by McGill Library. |
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