Molecular changes in the aging osteoblast

Aging is the consequence ofan array of phenotypic variations that appear to involve intrinsic or constitutional properties in all cells and systems, including qualitative and quantitative alterations in development, maturational structure and function. The aging process in bone involves a set ofchanges in bone cells differentiation, interaction and premature death. Osteoblasts are the cells most affected during the aging process in bone due to their complex mechanisms ofdifferentiation, their interaction with honnones and growth factors and their progression to apoptosis.

Identiferoai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.19466
Date January 2003
CreatorsDuque, Gustavo
PublisherMcGill University
Source SetsLibrary and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada
LanguageEnglish
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation
Formatapplication/pdf
CoverageDoctor of Philosophy (Division of Experimental Medicine)
RightsAll items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.
Relationalephsysno: 002011275, Theses scanned by McGill Library.

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