Objective. To develop predictive models for positive outcomes of upper and lower endoscopies in children. / Methods. Retrospective review of all endoscopies performed from January to December, 2000 at St. Justine Hospital. Predictive models for positive outcomes on endoscopy were constructed for upper and lower endoscopies separately using multiple logistic regression. / Results. Age greater than 13 years, hematemesis, epigastric tenderness and hypoalbuminemia were significant predictors of positive upper endoscopies. Male sex, age and rectal bleeding were significant predictors of positive lower endoscopies. Both models were significant at p < 0.0001 yet their receiver operating curves indicated that a model with sensitivity of 95% had a specificity of less than 40%. / Conclusion. Predictors of positive upper and lower endoscopy outcomes were found. The predictive models were statistically significant yet their performance did not reach clinical significance. A prospective, adequately powered study of predictors for endoscopy outcomes is needed to confirm these results.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.82301 |
| Date | January 2004 |
| Creators | Noble, Angela |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science (Department of Epidemiology and Biostatistics.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 002199146, proquestno: AAIMR12512, Theses scanned by UMI/ProQuest. |
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