Health is defined as a state of complete physical, mental and social well-being, and not merely the absence of disease. Quality of life refers to a person's perception of well-being and life satisfaction. Chronic liver failure can have significant negative impact on a patient's cognitive abilities and can cause physical debilitation. Thus, it is not surprising that cirrhotic patients often have severe impairment in their quality of life (QOL). From the perspective of the health care system, patient's health-related quality of life (HRQL) is the more relevant construct. Success of liver transplantation (OLT) is often measured by length of survival, as opposed to patient perceptions of personal health. / The primary objective of this study is to identify which of the Short-Form Health Survey (SF-36), EuroQuol (EQ-5D) VAS, and General Health Questionnaire-30 (GHQ-30) is the most responsive for detecting HRQL change for patients pre- and post-liver transplantation. The secondary objective is to compare the relative efficiency of the HRQL measures to traditional liver biochemistry parameters.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.82450 |
| Date | January 2005 |
| Creators | Wong, Philip, 1967- |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science (Department of Epidemiology and Biostatistics.) |
| Rights | All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated. |
| Relation | alephsysno: 002199138, proquestno: AAIMR12565, Theses scanned by UMI/ProQuest. |
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