Rationale. Hypertension occurs in 10% of pregnancies. Snoring is a marker for sleep apnea, and is a newly identified risk factor for gestational hypertension. Moreover, sleep apnea is an independent risk factor for hypertension in the non-pregnant population. I hypothesized that sleep apnea was associated with gestational hypertension. / Hypothesis. The prevalence of sleep apnea is higher among pregnant women with hypertensive pregnancies than among those without hypertension during pregnancy. / Design. Case-control study of 17 pregnant women with gestational hypertension and 33 pregnant women without hypertension, with matching by gestational age. Sleep apnea was ascertained by polysomnography. / Results. The crude odds ratio for the presence of obstructive sleep apnea, given the presence of gestational hypertension, was 5.6. The odds ratio was 7.5 (95% CI 3.5-16), based on a logistic regression model with adjustment for maternal age, gestational age, nulliparity, first pregnancy, and body mass index. / Conclusion. Gestational hypertension was strongly associated with the presence of obstructive sleep apnea.
| Identifer | oai:union.ndltd.org:LACETR/oai:collectionscanada.gc.ca:QMM.99328 |
| Date | January 2006 |
| Creators | Champagne, Katéri A. |
| Publisher | McGill University |
| Source Sets | Library and Archives Canada ETDs Repository / Centre d'archives des thèses électroniques de Bibliothèque et Archives Canada |
| Language | English |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Format | application/pdf |
| Coverage | Master of Science (Department of Epidemiology and Biostatistics.) |
| Rights | © Katéri A. Champagne, 2006 |
| Relation | alephsysno: 002562323, proquestno: AAIMR28473, Theses scanned by UMI/ProQuest. |
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