The thesis showed preliminary evaluation of novel biodegradable and biocompatible agmatine-containing PAA crosslinkers. Hydrogels fabricated by this crosslinker can obtain controllable stiffness and excellent cell adhesion. The PAA contained thermo-sensitive hydrogel reported here is first employed as filler for depressed defects in rats. Results showed that such hydrogel can be injectable and biocompatible, might become a new material in plastic surgery in the clinic. The thesis also demonstrated a novel macro gels with self-healing capability and biocompatibility. The reversible photodimerization and photocleavage reactivity of coumarin has been successfully imparted to the polymer. / February 2015
| Identifer | oai:union.ndltd.org:MANITOBA/oai:mspace.lib.umanitoba.ca:1993/30180 |
| Date | 08 January 2015 |
| Creators | Yu, Lianlian Jr |
| Contributors | Zhong, Wen (Textile Sciences) Xing, Malcolm (Mechanical Engineering), Wang, Quan (Mechanical Engineering) Cai, Jun (Electrical and Computer Engineering) |
| Source Sets | University of Manitoba Canada |
| Detected Language | English |
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