Spectral analysis of heart rate variability (HRV) has been applied
in many medical research to study autonomic nervous system
activity. In these studies, the researchers found that (i) ratio
of low frequency (LF) to high frequency (HF) spectrum power is a
useful measure of sympathetic/parasympathetic balance, and (ii)
low heart rate variability is an important risk factors for
patients. Therefore, continuous monitoring of the ratio and heart
rate variability have the potential to early detect physiological
deterioration of patients. This thesis consists of the following
two parts. In the first part, we establish control charts
monitoring heart rates and low HRV. Numerical method is applied
to compute exact control limits of the EWRMS and EWMV charts. The
distribution of the conventional LF/HF ratio statistic is
difficult to derive, significant of alterations in HRV parameters
can not be assessed efficiently. We resolve this problem in the
second part, a new equivalently useful ratio statistic is proposed
whose distribution can be derived more easily. Based on the
derived distribution, the probability control limits of the
proposed statistic are calculated. In application, we construct
Shewhart charts of the newly proposed ratio statistic and EWRMS,
EWMV charts of the heart rate variability to monitor the risk
factors of patients in vascular intensive care unit. Furthermore,
we define a risk score which combining the two risk factors
together, heart rate variability and LF/HF spectrum power ratio.
The results show that the higher risk scores corresponding to
patients after operation in severer condition.
| Identifer | oai:union.ndltd.org:NSYSU/oai:NSYSU:etd-0619101-192526 |
| Date | 19 June 2001 |
| Creators | Lai, Ju-Ja |
| Contributors | Mong-Na Lo, Kai-Sheng Hsieh, Meihui Guo, Chia-Yee Liu |
| Publisher | NSYSU |
| Source Sets | NSYSU Electronic Thesis and Dissertation Archive |
| Language | English |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0619101-192526 |
| Rights | off_campus_withheld, Copyright information available at source archive |
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