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Design of a programmable multi-parameter amplifier front-end for bio-potential recording

Home medical equipment becomes increasingly popular as VLSI fabrication technology advances. However, there are two important factors for realizing a miniaturized biochip: low noise [1] and low power. Firstly, physiological signals are very susceptible to interference while the amplitude of the signal is only a few millivolts or less. If the circuit cannot reject noise effectively, it is hard to amplify the signal and obtain the output voltage of the recording system accurately. Secondly, it is not convenient to replace the batteries frequently when using the portable measurement instrument for the patients. This thesis is focused on the measurement of physiological signals, such as electrocardiography (ECG) [2], electroneurogram (ENG) [3] and electromyography (EMG) [4] , and designing an all-in-one recording system to measure the different physiological signals in a chip. For this purpose, a programmable multi-parameter system for recording of the wide range of physiological signals is designed. The system provides two types of input transconductance stages, BiCMOS and CMOS. BiCMOS amplifiers provide high gain , low noise [5] and low offset voltage suitable for the small amplitude of the physiological signal. On the other hand, CMOS amplifiers provide practically infinite input impedance and ultra-low leakage current. The system also provides three selectable amplifier modes: (a) double-differential amplifier, (b) single-differential amplifier in channel 1, (c) single-differential amplifier in channel 2. The double-differential amplifier provides a high common-mode rejection and adjustable gain for each channel to further reduce common-mode interference. The single-differential amplifier (channel 1 or channel 2) in the recording system are also accessible as differential-input and single-ended output channels. Moreover, the system provides an offset compensation structure to prevent the amplifier from exceeding the input range. The offset compensation system can selectively be turned off to reduce the power consumption.

Identiferoai:union.ndltd.org:NSYSU/oai:NSYSU:etd-0830111-223310
Date30 August 2011
CreatorsLin, Yu-bin
ContributorsRobert Rieger ยก@, Chiu, Jih-Ching, Chung-Yao Kao, Tsang-Ling Sheu
PublisherNSYSU
Source SetsNSYSU Electronic Thesis and Dissertation Archive
LanguageEnglish
Detected LanguageEnglish
Typetext
Formatapplication/pdf
Sourcehttp://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0830111-223310
Rightsuser_define, Copyright information available at source archive

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