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Lecithin supplementation and free and esterified cholesterol in plasma

The effect of oral lecithin supplementation on plasma lipids
was investigated. Thirty-one healthy middle-aged men received 7.2
gm soy lecithin daily for two months. Blood was drawn both before
and after supplementation and analyzed for total and esterified
cholesterol, total and individual phospholipids, total lipids, triglycerides,
and lecithin:cholesterol acyltransferase (LCAT) activity.
Information on dietary intake, physical activity, smoking habits and
relative weight was also obtained.
The proportion of cholesterol ester increased significantly
(p < 0.01) with supplementation, as did LCAT activity (p < 0.025).
None of the other lipid parameters changed during the experimental
period. A positive correlation was found between LCAT activity and
the ratio of lysophosphatidyl choline to phosphatidyl choline.
Triglycerides were positively correlated with smoking and percent
of desirable weight, and negatively correlated with activity level. Higher proportions of cholesterol ester were associated with more
vigorous physical activity and with lower relative weights. / Graduation date: 1976

Identiferoai:union.ndltd.org:ORGSU/oai:ir.library.oregonstate.edu:1957/26977
Date18 March 1976
CreatorsHolden, Lisa Schweickhardt
ContributorsYearick, Elisabeth S.
Source SetsOregon State University
Languageen_US
Detected LanguageEnglish
TypeThesis/Dissertation

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