The aim of this study was to investigate the vitamin B-6 status of Saudi adult
males and compare the status between rural and urban subjects. Fifty-one adult male
subjects were recruited from urban (n=31) and rural (n=20) populations of Riyadh.
These subjects were reclassified to cigarette smokers (n=19), water pipe smokers
(n=5) and non-smokers (n=27). The study also investigated the intake of
macronutrients and selected micronutrients. In addition, the study investigated other
health indicators including Body Mass Index (BMI), hematocrit, hemoglobin, plasma
alkaline phosphatase activity and albumin concentration, urinary creatinine and urea
nitrogen excretion.
The mean of vitamin B-6 intake, B-6 to protein ratio, plasma pyridoxal phosphate
(PLP) concentration and urinary 4-PA excretion in urban group were 2.18 ± 0.62
mg/day, 0.022 ± 0.008 mg/g, 39.3 ± 18.0 nmol/L and 4.6 ± 2.3 μmol/day, respectively. In rural group, these measures were 2.15 ± 0.65 mg/day, 0.021 ± 0.004 mg/g, 40.5 ± 14.6 nmol/L and 4.4 ± 2.3 (μmol/day, respectively. These measures indicated adequate
status with no significant difference between the two groups. The mean intake of
calcium, folate, vitamin D, zinc and dietary fiber was lower than recommendation of
the Dietary Reference Intakes (DRI) in both groups. Health indicators were within
normal range except for BMI, which indicated a prevalence of overweight and obesity
in both urban (27.1 ± 5.5 Kg/m²) and rural (28.2 ± 6.0 Kg/m²) subjects.
Comparison of the three smoking groups showed that the water pipe smokers
compared to cigarette smokers and non-smokers groups had significantly higher mean
intake of vitamin B-6 (2.51 ± 0.73 mg/day), which resulted in higher concentrations of
plasma PLP, pyridoxal (PL), red blood cells PLP and urinary 4-PA (54.9 ± 23.1
nmol/L, 21.5 ± 10.0 nmol/L, 33.7 ± 8.5 nmol/L and 6.9 ± 4.7 μmol/day, respectively).
Cigarette smokers had significantly lower concentration of plasma PLP (30.9 ± 12.5
nmol/L) compared to non-smokers (40.0 ± 12.9 nmol/L) without a significant
difference in vitamin B-6 intake. Hematocrit and hemoglobin were significantly higher
in smokers (50 ± 3% and 167 ± 11 g/L, respectively) compared to non-smokers (48 ±
3% and 160 ± 9 g/L, respectively). The results of this study suggest that vitamin B-6
status of adult males in Riyadh is adequate with no urban vs. rural variation. / Graduation date: 2004
| Identifer | oai:union.ndltd.org:ORGSU/oai:ir.library.oregonstate.edu:1957/27116 |
| Date | 11 August 2003 |
| Creators | Al-Assaf, Abdullah |
| Contributors | Leklem, James E. |
| Source Sets | Oregon State University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis/Dissertation |
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