The concept of genetic penetrance, "the frequency of manifestation of a
genetic factor," was introduced by Timofeef-Ressovsky (Naturwissenschaften
19:493,1931). Incomplete penetrance has been used to explain the absence
of phenotypic expression when otherwise anticipated. Studies of Embryonic
Chick Edema, ECE (Poultry Sci. 77(suppl. 1):69, 1998) have been conducted
in order to determine the origins for incomplete penetrance of this disorder.
ECE was originally reported as the expression of two autosomal recessive loci
with incomplete penetrance. Pedigreed inter se mating of ECE individuals
have resulted in familial incidences ranging for 0 to 100% with a mean of
48.2% in the most recent generation selected. With consideration of a third
contributing locus, current data and 2 sets of previous data were evaluated.
Heterogeneity and pooled chi square tests when applied to the data sets
support the hypothesis that ECE was the result of two completely dominant
loci and one homozygous recessive locus. / Graduation date: 2004
| Identifer | oai:union.ndltd.org:ORGSU/oai:ir.library.oregonstate.edu:1957/31600 |
| Date | 21 November 2003 |
| Creators | Phillips, Wenona Anne |
| Contributors | Savage, Thomas F. |
| Source Sets | Oregon State University |
| Language | en_US |
| Detected Language | English |
| Type | Thesis/Dissertation |
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