Chilean red chili peppers contaminated with aflatoxins were reported in a previous study. If the development
of gallbladder cancer (GBC) in Chile is associated with a high level of consumption of aflatoxin-contaminated red
chili peppers, such peppers from other countries having a high GBC incidence rate may also be contaminated
with aflatoxins. We aimed to determine whether this might be the case for red chili peppers from Bolivia and
Peru. A total of 7 samples (3 from Bolivia, 4 from Peru) and 3 controls (2 from China, 1 from Japan) were
evaluated. Aflatoxins were extracted with acetonitrile:water (9:1, v/v) and eluted through an immuno-affinity
column. The concentrations of aflatoxins B1, B2, G1, and G2 were measured using high-performance liquid
chromatography (HPLC), and then the detected aflatoxins were identified using HPLC-mass spectrometry. In
some but not all of the samples from Bolivia and Peru, aflatoxin B1 or aflatoxins B1 and B2 were detected. In
particular, aflatoxin B1 or total aflatoxin concentrations in a Bolivian samples were above the maximum levels for
aflatoxins in spices proposed by the European Commission. Red chili peppers from Bolivia and Peru consumed
by populations having high GBC incidence rates would appear to be contaminated with aflatoxins. These data
suggest the possibility that a high level of consumption of aflatoxin-contaminated red chili peppers is related to
the development of GBC, and the association between the two should be confirmed by a case-control study.
| Identifer | oai:union.ndltd.org:PERUUPC/oai:repositorioacademico.upc.edu.pe:10757/311040 |
| Date | 08 January 2014 |
| Creators | Asai, Takao, Tsuchiya, Yasuo, Okano, Kiyoshi, Piscoya, Alejandro, Yoshito Nishi, Carlos, Ikoma, Toshikazu, Oyama, Tomizo, Ikegami, Kikuo, Yamamoto, Masaharu |
| Publisher | Asian Pacific Organization for Cancer Prevetion |
| Source Sets | Universidad Peruana de Ciencias Aplicadas (UPC) |
| Language | English |
| Detected Language | English |
| Type | info:eu-repo/semantics/article |
| Format | application/pdf |
| Source | Universidad Peruana de Ciencias Aplicadas (UPC), Repositorio Académico - UPC |
| Rights | info:eu-repo/semantics/openAccess |
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