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Antiplasmodial β-hydroxydihydrochalcone from seedpods of Tephrosia elata

From the seedpods of Tephrosia elata, a new β-hydroxydihydrochalcone named (S)-elatadihydrochalcone was isolated. In addition, the known flavonoids obovatachalcone, obovatin, obovatin methyl ether and deguelin were identified. The structures were determined on the basis of spectroscopic evidence. The crude extract and the flavonoids obtained from the seedpods of this plant showed antiplasmodial activities. The literature NMR data on β-hydroxydihydrochalcones is reviewed and the identity of some of the compounds assigned β-hydroxydihydrochalcone skeleton is questioned.

Identiferoai:union.ndltd.org:Potsdam/oai:kobv.de-opus-ubp:4443
Date January 2009
CreatorsPeter, Martin G., Muiva, Lois M., Yenesew, Abiy, Derese, Solomon, Heydenreich, Matthias, Akala, Hoseah M., Eyase, Fredrick, Waters, Norman C., Mutai, Charles, Keriko, Joseph M., Walsh, Douglas S.
PublisherUniversität Potsdam, Mathematisch-Naturwissenschaftliche Fakultät. Institut für Chemie
Source SetsPotsdam University
LanguageEnglish
Detected LanguageEnglish
TypePostprint
Formatapplication/pdf
SourcePhytochemistry letters 2 (2009), 3, S. 99 - 102, DOI 10.1016/j.phytol.2009.01.002
Rightshttp://opus.kobv.de/ubp/doku/urheberrecht.php, Volltextzugriff: Universitätsverlag - eingeschränkter Zugriff

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