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Evaluating Alternate Anthropometric Measures as Predictors of Incident Type 2 Diabetes Mellitus (T2DM). The Insulin Resistance Atherosclerosis Study (IRAS)

The goal of this study was to compare different anthropometric measures in terms of their ability to predict T2DM and to determine whether predictive ability was modified by ethnicity. Anthropometrics were measured at baseline on 1073 non-Hispanic Whites (nHW), African Americans (AA) and Hispanics (HA), of which 146 developed T2DM after 5.2 years. Logistic regression models were used with areas under the receiver operator characteristic curve (AROC) comparing the prediction of models. Overall, there was no clear distinction between measures of overall and central obesity in terms of T2DM prediction. Waist-height ratio (AROC=0.678) was the most predictive measure, followed by BMI (AROC=0.674). Results were similar in nHW and HA, although, in AA, central adiposity measures best predicted T2DM. Measures of central and overall adiposity predicted T2DM to a similar degree, except in AA where central measures were most predictive.

Identiferoai:union.ndltd.org:TORONTO/oai:tspace.library.utoronto.ca:1807/17197
Date24 February 2009
CreatorsMacKay, Meredith
ContributorsHanley, Anthony James Gordon
Source SetsUniversity of Toronto
Languageen_ca
Detected LanguageEnglish
TypeThesis
Format646248 bytes, application/pdf

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