Introduction: This thesis prospectively evaluated the cognitive and functional outcomes and health-related quality of life of children admitted urgently to a Pediatric Intensive Care Unit (PICU) at the Hospital for Sick Children.
Methods: The primary outcome was the Vineland Adaptive Behavioural Scale (VABS-2) measured at 1-month and secondary outcomes were health-related quality of life, daily functioning, and caregiver perceptions.
Results: 56 children and 66 caregivers were enrolled; 42 (75%) patients and 49 (74%) caregivers completed the 1-month assessment. Children in the PICU had a mean VABS-2 score of 85(+25). Daily functioning outcomes did not significantly change from baseline to 1-month. In comparison to baseline, children had significantly reduced health-related quality of life at 1-week but no significant change was found at 1-month.
Discussion: Children surviving PICU have significant cognitive morbidity and reduced health-related quality of life that is exacerbated by more intense modes of resuscitation and increasing severity of illness.
| Identifer | oai:union.ndltd.org:TORONTO/oai:tspace.library.utoronto.ca:1807/18286 |
| Date | 15 January 2010 |
| Creators | Ebrahim, Shanil |
| Contributors | Parshuram, Christopher |
| Source Sets | University of Toronto |
| Language | en_ca |
| Detected Language | English |
| Type | Thesis |
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