Little is known about the early recovery of functional outcomes in the lung transplant population. This thesis investigated skeletal muscle strength, functional exercise capacity, health-related quality of life and daily physical activity pre- and early post-lung transplantation in a cohort of fifty participants.
Significant functional limitations were observed pre-transplant, however levels of physical activity were higher on rehabilitation days as compared to non-rehabilitation days. Post-transplant, improvements in functional exercise capacity and physical activity lagged behind the early improvements in pulmonary function and health-related quality of life. Muscle strength was reduced at hospital discharge compared to pre-transplant levels, but improved to pre-transplant levels by three months post-transplant.
In summary, significant functional limitation exists pre-transplant, and lung transplantation leads to significant improvement of functional outcomes; however functional recovery occurs at different time periods and to varying degrees, and does not reach levels of a healthy reference population by three months post-lung transplant.
| Identifer | oai:union.ndltd.org:TORONTO/oai:tspace.library.utoronto.ca:1807/33586 |
| Date | 27 November 2012 |
| Creators | Wickerson, Lisa Michelle |
| Contributors | Brooks, Dina |
| Source Sets | University of Toronto |
| Language | en_ca |
| Detected Language | English |
| Type | Thesis |
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