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Texture Analysis of Optical Coherence Tomography Speckle for the Detection of Tissue Variability

About 50% of cancer patients are treated with X-ray radiation therapy; however, with current treatment feedback, the effects and the efficacy of the treatment are generally detected several weeks/months after treatment completion. This makes the adjustment of the treatment based on early response, and identification of non-responding patients, nearly impossible.
In this thesis a novel method combining optical coherence tomography and a gamut of image analysis methods is explored as a potential approach to detecting tissue variability. Applying texture analysis to the optical coherence tomography images may allow for the tracking of radiation therapy induced cell microstructural changes in cancer patients and help in the adjustment of treatment based on early response.

Identiferoai:union.ndltd.org:TORONTO/oai:tspace.library.utoronto.ca:1807/43086
Date04 December 2013
CreatorsLindenmaier, Andras
ContributorsVitkin, Alex
Source SetsUniversity of Toronto
Languageen_ca
Detected LanguageEnglish
TypeThesis

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